Medicine March 2012 FCPS Part-1 Paper

1. Tumor spread by:
a. Migration of tumor cells
b. Breakdown of e-cadherin
c. sepeation of tumor cells from one another
d. Damaging extracellular matrix
e.

2. What is most common cause of congenital hypothyroidism:
a. Maternal iodide deficiency
b. Inborn error of metabolism
c. Defective embryogenesis
d. Antibodies against thyroid hormone crossing placenta
e.

3. Diabetic pat taking oral hypoglycemic drugs complain of abdominal fullness, which drug can b given to decrease gastropresis
a. Omeprazol
b. Cimetidine
c. Antacids
d. Metclopramide
e.

4. On motor bike accident fracture of neck of humerus n can,t abduct his arm.due to
a. Axillary nerve
b. Long thoracic nerve
c. Musculocutaneous nerve
d.
e.

5. Regarding trachea
a. Gap in the C shape cartilages are lying anteriorly
b. 15 cm in length
c. Recurrent laryngeal nerve pases anteriorly
d. Isthmus of thyroid lying in front of 4rt or 5th tracheal ring
e. Starts at the lower border of cricoid cartilage

6. Release of acid from stomach is mediated through
a. H1 receptor
b. H2 receptor
c. food in stomach
d.
e.

7. Diaphragm is supplied by
a. C3
b. C3,4,5
c. C4,5
d. C4,5,6
e.

8. A female at 36weeks gestation cmwith bili;20mg/dl raised SGPT & SGOT.she has returned from remote village. What can b the cause of infection?
a. HAV
b. HBV
c. HCV
d. HEV
e.

9. What is the structure arches around the root of left lung
a. Azygus vein
b. Arch of aorta
c. Left phrenic nerve
d. Left vagus nerve
e. Left recurrent laryngeal nerve

10. Regarding ESR decreased by increase in which of the following
a. Increase plasma globulin
b. Increase fibrinogen
c. Increase plasma Albumin
d. Increase globulin and albumin ratio
e. Temperature

11. Best example of pharmaco kinetics drug drug interaction:
a. Iincrease action of procain by epinephrine
b. Increase action of........... by Calcium
c. Toxicity of lithium with thiazide diuretics
d. Reverse the action of aspirin by NaHCO3
e. Reverse the action of Morphine by Naloxone

12. Following veins drain into coronay sinus, which vein continues as coronary sinus
a. Middle cardiac vein
b. Great cardiac vein
c. Anterior cardiac vein
d. Oblique vein
e.

13. Notochord arises from
a. Ectoderm
b. Mesoderm
c. Endoderm
d.
e.

14. Thyroid is derived from
a. Ectoderm
b. Mesoderm
c. Endoderm
d.
e.

15. Which one of the following is a chemical carcinogen
a. Alpha 1 antitrypsin
b. Benzidine
c. Ethyl alcohol
d. Propyl alcohol
e.

16. Contractile unit in skeletal muscle is between
a. h discs
b. z lines
c. t tubules
d.
e.

17. A/P radiograph of chest which structure forms right border of heart
a. SVC
b. IVC
c. Right ventricle
d. Arch of aorta
e. Left Atrium

18. 60 percent of work of breathing
a. is to overcome elastic recoil of lungs
b. Counteract chest wall compliance
c. Resistance offered by small size bronchi
d. Resistance by large bronchi
e.

19. Regarding nerve supply to skeletal muscle contains
a. 60%motor 40%sensory fibers
b. 40%motor 60%sensory
c. 60%motor 40%sensory and few postganglionic sympathetic fibers
d.
e.

20. Thirst stimulated by
a. ECF volume depletion
b. ICF volume depletion
c. Salt depletion
d.
e.

21. Regeneration least effected by
a. Diabetes
b. Infection
c. Uv light
d. corticosteroid
e.

22. In downs syndrome at 40 years of age
a. Alzhiemers disease
b. Stroke due to essential hypertension
c. Upper motor neuron lesion
d. Lower motor neuron lesion
e.

23. Primary cartilaginous joint
a. Costochondral
b. Teeth and jaw
c. Inferior tibiofibular joint
d. Symphysis Pubis
e.

24. Epinephrine reuptake by
a. Diffusion and reuptake
b. Diffusion, reuptake and enzyme catalysis
c. Diffusion
d. Reuptake
e. Enzyme catalysis

25. 2 yr old child presented with anemia and has hyper segmented neutrophil, MCV raised, how will you confirm your diagnosis
a. Intrinsic factor antibodies
b. Vit b12 level
c. Transcobalamin
d.
e.

26. Thrombus formation triad
a. Endothelial damage, slow blood flow, altered blood constituents
b. Endothelial damage; high blood flow, fibrin
c. Endo damage eddy blood flow
d. Plasma high blood flow
e.

27. After 6 hours of myocardial infarction which enzyme level most raised
a. CPK
b. LDH
c. ALT
d. AST
e. ALKALINE PHOSPHATASE

28. In adult female breast atrophy is commonly due to decrease
a. Estrogen
b. Estrogen and progesterone
c. Progesterone
d. Prolactin
e.

29. Patient taking MAO inhibitors, taking which of the following could cause hypertensive crisis?
a. Coffee
b. Chocolate
c. Cola
d. Pine apple
e. String beans

30. Left kidney is not related anteriorly to which of the following structures?
a. Diaphragm
b. Stomach
c. Pancrease
d. Spleen and splenic vessels
e. Splenic flexure of transverse colon

31. A 30 year man participated in marathon race the most common hormone changes you will find
a. Low Insulin, High Glucagon
b. Low Insulin, Low Glucagon
c. High Insulin, High Glucagon
d. High Insulin, Low Glucagon
e.

32. 2x2 table in biostats?
a. T-Test
b. Chi Square Test
c.
d.
e.

33. Which of the following lymphoid structure does NOT contain lymph nodules:
a. Spleen
b. Lymph node
c. Thymus
d. Payer's patches
e. Tonsils

34. A person has pH 7.48, CO2 66 and HCO3 27 . What is the diagnosis
a. Acute respiratory acidosis
b. Acute metabolic acidosis
c. Partially compensated respiratory acidosis
d. Partially compensated metabolic acidosis
e. Partially compensated metabolic alkalosis

35. A patient suffers from appendicitis. Peripheral blood shows leukocytosis. Pain will be mediated by
a. IL 1 and TNF alpha
b. Bradykinin and prostaglandin E
c. Serotonin
d. IL 6
e. enkephalin

36. In myocardial infarction, which earliest change occurs in formation of aschoff bodies
a. Fibrinoid necrosis
b. Inflamaton
c. Giant cell
d. Eosinophilia
e.

37. Regarding movements of foot:
a. Inversion n eversion occur at subtalar joint
b. Tibialis anterior n tibialis posterior cause inversion
c. Peronei cause eversion
d. Aschli tendon plays imp role when we r standing on toes
e.

38. 45y lady comes with vaginal bleeding doc advise her for hysterectomy due to premalignant condition which is it?
a. Atypical endometrial hyperplasia
b. Complex endometrial.....
c. Simple endometrial...
d. Squamous metaplasia
e.

39. Child with generalized edema and proteinurea 6g per day which part of the kidney involved
a. Interstitium
b. Basement membrane
c. Collecting tubules
d. Proximal convulated tubules
e. Distal tubules

40. Young female developed acute renal failure after post partum hemorrhage. which part of the kidney is most likely damaged
a. Proximal convuluted tubules
b. Loop of henle
c. Collecting tubules
d. Dital convuluted tubules
e.

41. Regarding neutrophil correct
a. Migrate into and out of blood stream
b. More phagocytic in bloodstream
c. Decrease in infective conditions
d. Decrease when corticosteroid given
e.

42. Initial response to tissue injury is:
a. Vasoconstriction
b. Clot formation
c. Platelet adherence
d.
e.

43. Hypoxia causes vasoconstriction in
a. Pulmonary vasculature
b. Heart
c. Brain
d. Kidney
e.

44. High levels of protein associated with
a. Chylomicrons
b. HDL
c. VLDL
d. LDL
e.

45. After 6 hours of myocardial infarction which enzyme level most raised
a. CPK
b. LDH
c. ALT
d. AST
e. ALKALINE PHOSPHATASE

46. Blood supply of motor cerebral cortex
a. Anterior and middle cerebral artery
b. Anterior and posterior cerebral artery
c. Basillar artery
d.
e.

47. Most common cause of liver cirrhosis in an adult male?
a. Alcoholism
b. Hepatitis B
c. Hepatitis C
d. Hepatitis A
e. Hepatitis D

48. What is most characteristic of cerebral motor cortex
a. is present in frontal lobe
b. Doesn't receive any sensory input
c. is essential to carry out voluntary movements
d. essential for stretch reflex
e.

49. 3rd ventricle, what is most inappropriate
a. choroid plexus is present in its floor
b. choroid plexus is supplied by internal carotid and basillary artery
c. is connected to lateral ventricles via interventricular formina
d. is connected to 4th ventricle via cerebral acqueduct
e. present in midbrain

50. Diff b/w first n second heart sounds...
a. Frequency
b. Duration
c. With carotid pulse
d.
e.

51. Distribution of drug enhanced by?
a. Ionized state
b. Lipid solubility
c. Electric equivalence
d.
e.

52. Right bronchus
a. Is shorter
b. Is vertical
c. is infront of pulm artey
d. is infront of pulm vein
e.

53. Fasting blood sugar of patient is 6.8 mol(122mg/dl) after 1 hour of gtt its 10.9 mol and later after 2 hours post prandial it was 10.7 mol(194 mg/dl) what is the diagnosis..
a. Diabetes mellitus
b. Impaired gluc tolerance
c. long lag phase
d. Secondary diabetes mellitus
e.

54. Ischemia in Diabetes mellitus commonly results from
a. Dry gangrene
b. Gas gangrene
c. Endarteritis obliterans
d. Wet gangrene
e.

55. Rods and cones wid excitatory potentials to ganglion and bipolar cells...which neurotransmitter?
a. GABA
b. Glycine
c. Glutamate
d.
e.

56. Which structure doesn’t lie deep to the parotid gland?
a. Internal jugular vein
b. Internal carotid artery
c. Pharynx
d. Parotid duct
e. x, xi nerves in the carotid sheath

57. Bad news, when delivered to patient, should ideally be
a. At bedside
b. All the staff involved in patient's care should be present
c. In front of all family members
d. In doctor's office, in a formal session, in environment of exclusivity
e.

58. Regarding counseling, when done to pts, is good for
a. Their friends
b. Family members
c. Other pts
d. Themselves
e.

59. Which of the following tumors doesn’t cause distant metastases?
a. basal cell Ca
b. dysgerminoma
c. verucous carcinoma
d. Squamous cell carcinoma
e.

60. cx shows mild dysplasia with squamous vacuoles:
a. CIN 1
b. CIN II
c. CIN III
d. Ca in situ
e. HPV

61. Which one of the following organ is present inside the peritoneal cavity?
a. fallopian tubes
b. ovary
c. gonads
d. first part of the duodenum
e. round ligament of uterus

62. What is the most common cause of increased vascular permeability?
a. Inflammation
b. Trauma
c. Immunological
d. Allergy
e.

63. Regarding Vitamin K
a. is a water soluble vitamin
b. produced by intestinal bacteria
c. present in large amount in human and cow's milk
d. When given in neonatal hemorrhage, prevents coagulation
e.

64. Psoas muscle
a. originate from all lumbar vertebra
b. present b/w lumber plexus
c. passes in front of inguinal ligament
d.
e.

65. Half life of carboxyhaemaglobin.
a. 5 min
b. 2hr
c. 6 hr
d.
e.

66. Regarding icf
a. 2/3 of tbw
b. 1/3 of tbw
c.
d.
e.

67. Which of the following non hairy regions does not have sebacous glands?
a. glans and prepuce of penis
b. labia minora
c. margins of lips
d. palms and soles of feet
e. nipple

68. ESR decreases with increase in:
a. cholesterol in blood
b. inc. globulin
c. plasma albumin
d. fibrinogen
e. temperature

69. Hypokalemia causes which of the following...
a. Hyperpolarization
b. Hyperexcitability
c. decrease in height of action potential
d.
e.

70. An alcoholic patient comes with wernikes korasakoff syndrome. It could be due to def of which of the following vitamins
a. B1
b. A
c. D
d. K
e. C

71. In 90 percent of anthrax infections
a. Hemorrhagic pneumonia
b. gatrointestinal hemorrhage
c. skin lesions
d. bacteremia
e.

72. Not related to spinal cord
a. ant gray horn
b. latearl lemniscus
c. posterolateal sulcus
d. gray commisure
e.

73. Patient presented with painless heamaturia along with fever, night sweats for 2 months, ultrasound abdomen plain is normal, diagnosis is
a. Renal Cell Carcinoma
b. Acute Pyelonephritis
c. Renal tuberculosis
d. Acute tubular Necrosis
e.

74. A patient with cervical lymphadenopathy, CXR shows Bilateral Hilar Lymphadenopathy. Biopsy shows caseating granulomaous pattern, diagnosis is
a. Sarcoidosis
b. Tuberculosis
c.
d.
e.

75. A 21 year old having severe Ulcerative Colitis,which of the following is indicated
a. Azathioprine
b. IV Corticosteroides
c. Sulfasalazine
d.
e.

76. In which of the following conditions,atrial repolarization is evident on ECG
a. 1st degree heart block
b. 3rd degree heart block
c. MI
d. Deep inspiraion
e.

77. Which of the following suppress GH release?
a. Puberty
b. Sleep
c. Somatomedin
d. Starvation
e. Stress

78. Which organ has a highest arteriovenous shunts
a. liver
b. lungs
c. heart
d. kidneys
e.

79. If ejection fraction is increased there will be
a. dec end-systolic volume
b. dec end-diastolic volume
c.
d.
e.

80. Amoebic liver abscess spread to lungs by
a. Direct
b. Lymphatics
c. Haematogenous
d. through diaphragm
e.

81. A pregnant lady has mitral stenosis,, to prevent atrial fibrillaton treatment is
a. im heparin
b. iv heparin
c. heparin and oral anticoagulant
d. oral anticoagulant
e.

82. There was some question from biostats that which is most inappropriate?
a. something was abt variance
b. experimental p<0.05
c. exploratory p<0.01
d. analysis of variance that it can be done by one thing
e.

83. Root value of knee jerk
a. L3 L4
b. s1
c. L1,2
d.
e.

84. A boy engulfs peanut and it got stuck in the air way where would it occlude?
a. right main bronchus
b. right middle broncus
c. right lower bronchus
d. left lower bronchus
e.

85. Which of the following is a tumour supressor gene?
a. Ras
b. bcl2
c. ABL
d.
e.

86. Acidophillic cytoplasm with basophilic granules, structure less material in center, outline irregular
a. karyolysis
b. hydrops degeneration
c. apoptosis
d. hydrolysis
e.

87. Cyclosporin acts by
a. stimulating production of NK cells
b. modifying maturation of T cells
c. inhibiting NK cells
d.
e.

88. How many ATPs are produced after complete metabolism of one molecule of Glucose?
a. 30
b. 32
c. 38
d. 40
e. 44

89. Female child born then sent home. 15 hours later she presented with cyanosis + weak pulse & diagnosis?
a. VSD
b. TRANSPOSITION OF GREAT VESSELS with no communication like VSD/ASD
c. hypoplastic Left ventricle
d. TOF
e. PDA

90. most powerful stimulus for rennin
a. dec NA Cocent to tbules
b. hypotention
c. sympathetic stimulation
d.
e.

91. Dietary fibers
a. Collagens
b. Peptidoglycans
c. Pectin
d. Starc
e.

92. Lymph flow from the foot is
a. increased when an individual rises from the supine to the standing position
b. increased by massaging the foot
c. increased when capillary permeability is decreased
d. decreased when the valves of the leg veins are incompetent
e. decreased by exercise

93. Which of the following is not synthesized in both endocrine glands and the brain?
a. Somatostatin
b. Cortisol
c. Dopamine
d. ACTH
e. Oxytocin

94. Regular rhythmic fluctuations in electrical activity are observed in the cerebral cortex and thalamus. In addition, they are seen in the
a. mediobasal portion of the hypothalamus
b. cerebellar cortex
c. midbrain reticular formation
d. amygdale
e. pons

95. In a healthy, alert adult sitting with the eyes closed, the dominant EEG rhythm observed with electrodes over the occipital lobes is
a. delta (0.5-4 Hz)
b. theta (4-7 Hz)
c. alpha (8-13 Hz)
d. beta (18-30 Hz)
e. fast, irregular low-voltage activity

96. A person cannot differentiate between red n green colour while making presentation on computer, what is the most likely defect in this patient ?
a. Absent rods.
b. Absent cones.
c. macula lutea
d.
e.

97. What will be the symptoms if there is leison in left optic radiation?
a. Blind left eye.
b. rt.homonymous hemianopia.
c. bitemporal hemianopia.
d. binasal hemianopia.
e. lt.homonymous hemianopia

98. In right shift of oxygen dissc. curve the most likely value of T50 would b?
a. 20
b. 18
c. 26
d. 35
e.

99. The part of basal nuclei is.........?
a. putamen.
b. amygdolid.
c. Subthalamus
d. Hypothalamus
e.

100. Isoelectric segment of ECG during which the complete ventricular depolirization occurs
a. QRS
b. QT SEG
c. ST seg
d.
e.

101. 2nd part of duodenum is crossed anteriorly by ......
a. mesocolon attachment
b. left renal vein
c. sup mesenteric artery
d. portal vein
e.

102. adult polycystic kidney disease
a. autisomoal dominant
b. aut.ressecive
c. x linked
d.
e.

103. A male 60 yr Generalized lymphadenopathy, on peri, smear lymphocytes looks mature cell .........
a. CLL
b. CML
c. ALL
d.
e.

104. Damage to median nerve......
a. loss of abduction of thumb
b. loss of adduction of thumb
c. loss off sensattion on lateral side of hand
d.
e.

105. CSF composition approprate is .........
a. 20_40mg/protein
b. Sodium 130 meq/ml
c. Glucose 120mg/dl
d.
e.

106. Internal capsule inapprorate is........
a. ant, and post. limb contains cortiospinal n corticocerbellar fiber
b. sensory fibers pass thru ant limb
c. corona radiate transmit impulses to cortex
d.
e.

107. Primordial germ cells deriveted from..
a. wall of yolk sac.
b. Amnion
c. Trophoblast
d. Deciduas
e.

108. during sleep hormone level is more than awake time
a. cortisol
b. ADH
c. epinephrine
d.
e.

109. anarobes infectionall all true execpt.......
a. granuloma formation
b. gangrene
c. food poisoning
d. necrosis
e. lock jaw

110. male 40 yr,15kg overwt with 20mmol blood sugar i treatment in addition to diet and excirse is
a. biguanides
b. glybenclamide
c. acarbose
d.
e.

111. Myasthenia garvis diz is......
a. type 2 H.S reaction
b. type 1
c. type 3
d. type 4
e.

112. poststreptococcal G.N is,,,,
a. type 2 H.S reaction
b. type 1
c. type 3
d. type 4
e.

113. Water flow from plasma to interstial fluid
a. filtration.
b. with sodium
c. active process
d. facilitated transport
e.

114. lymph filtration in spleen occurs in
a. penicillus arteries
b. trabicular
c. centre
d. peripheral
e.

115. Venous blood from the leg is increased during exercise,,
a. muscle contration of leg
b. valve in veins may be
c. intra thoracic pressure
d.
e.

116. Optic chiasma lesion causes..
a. bitemporal hemianopia
b. rt homonymeous hemianopia
c. lt..homonymeous hemianopia
d.
e.

117. father A ,,mother AB ,,fetus will never have blood group ……….
a. O
b. B
c. AB
d. A
e.

118. Mother –ve , father +ve 1st child with hepatospleenomegaly now 2nd child (erythroblastosis fetalesis),, baby has blood group….
a. O+ve
b. O-ve
c. B-ve
d.
e.

119. Pituitary gland not related with…..
a. facial nerve
b. sphenoid sinus
c. cavvernous sinuus
d. optic chiasma
e.

120. lady with PPH can not lactate her baby inspite of willing for lactation due to
a. sheehans synd..
b. anemia
c. fibroid
d. endometrial hyperplasia
e.

121. Female patient having ch, renal failure ,,best donor for transplatation ..
a. twin
b. husband
c. step sister
d. step brother
e.

122. In saliva bactriocidal agent is ……..
a. lysozymes
b. lysosome
c. acid
d. amylin
e. IgA

123. Rationale treatment of essenial HTN
a. alpha blkers
b. aldosterone
c. Angiotensin receptor blocker
d.
e.

124. Antibiotic given with serum conc, mointering ..
a. vancomycin
b. cyclosporine
c. omeprazole
d.
e.

125. Gardeners spraying inscticieds become sunconseous, salivation. drug to be given to antagonize symptoms ….
a. Pralidoxime
b. Atropine
c. Epinephrine
d.
e.

126. Adrenal glands blood supply most inappropriately..
a. all branches of arteries from aorta.
b. 1 branch from renal art
c. 1 br from phrenic
d.
e.

127. Nephrotic synd, with Generalized .edema due to….
a. dec, colloidal osmotic pressure
b. dec hydrostatic pressure
c. dec salt retention
d.
e.

128. ADH dec. by ……
a. Alcohol
b. Aldosterone
c. inc salt
d. decrease body water
e. starvation

129. PPI’s drug is …
a. omeprazole.
b. Cimetidine
c. Metoclopramide
d.
e.

130. H2 blockers …
a. dec HCL secretion
b. delay gastric emptying
c. inc hcl
d.
e.

131. Which is not immunosuprresnt…?
a. anticholerngic agent
b. corticosteroid
c. methotrexate
d.
e.

132. Which is not malignant lesion
a. Osteomlytis
b. Ulcerative colitis
c. Erythroplakia
d. sarcoidosis
e.

133. Swallowing stage…
a. Palantopharngeus muscles moves laterally
b. Larynx moves down
c. Palate move downwards
d.
e.

134. Basophilia of cell due to…
a. RER
b. golgi bodies
c. nnucleus
d.
e.

135. CIN of cervix most easy cheaper and valuable tst ..
a. pap smear
b. ultrasound
c. D n C
d.
e.

136. Correct about ureter………
a. enter rt angle in blabber
b. lies above utrine artery
c. is not close to cervix
d. present in broad ligament
e. posteriorly external ilaic vessels

137. regarding posteror mediastinum,,,,
a. aorta gives 9 post intercostal br
b. all intercostals veins drain into azygous vein
c. Thoracic duct turn to left side
d.
e.

138. 3rd part of subclavian artery anyersum swelling present in…
a. ant triangle
b. post triangle
c. axilla
d.
e.

139. Ventilation is very high at ….
a. apex of lung
b. base of lung
c. middlle zone
d.
e.

140. Pacemaker for cerebral cortex which show changes on EEG ….
a. Thalamus
b. reticular formation
c. hypothalamus
d.
e.

141. Nigrostratail fibers secrete neurotransmitter …
a. dopamine
b. Ach
c. Seotonin
d.
e.

142. Hormone causing Gluconeogenesis …
a. glucogan.
b. GH
c. ADH
d. Insulin
e.

143. Patient with fever ,joint pain ,chest infection, anemia,, HB type present will be
a. HB ss
b. HBsc
c. HB A2
d.
e.

144. Ac ventricular failure, resp distress, drug of choice is…
a. i/v frisemide
b. dopamine
c. streptokinase
d. oxygen
e.

145. Thyroid gland ..
a. Histological active follicles contain more colloid
b. start at uppper border of thyroid cartilage
c. isthamus at c123
d.
e.

146. Sympathetic block to urinary baldder, which will result??
a. pain n filling sensation lost
b. unable to empty bladder
c. inc tone of int.bladder sphincter
d. dec tone of ext.bladder sphincter
e. inc male fertility

147. Vagal stimulation result in..
a. inc gasticc emptying
b. dec gasticc emptying
c. block acid secretion
d.
e.

148. Tumor with least likely metastasis
a. BCC
b. SCC
c. lymphoma
d.
e.

149. Which of the following drug irreversibly blocks platelet action…
a. asprin
b. naproxen
c. diclofenac
d.
e.

150. patient wth BT prolong ,normal CT ,normal Aptt with clott retriction problem
a. afibrinogenmia
b. thrompocytopenia
c. hemophilia
d.
e.

151. FEMALE hyperthoriodism with palpitaion and tachycardia, pulse rate 110, all these findings are due to…
a. beta adrenergic response
b. Alpha adrenergic
c. vagus stimulation
d.
e.

152. Pul.O2 toxicity result from
a. prolong o2 therapy
b. inc PCO2
c. at high altitude
d. in under water
e.

153. Clinically, GFR is measured by
a. creatine
b. inulin
c. PAH
d.
e.

154. About ansa cervicalis……..all are correct except
a. supply to carotid body
b. c1,2,3
c. joins hypoglossal
d. supply thyrohyoid muscle
e.

155. Inappropriate for type 2 Hyper.Sensitivity..
a. mast basophiles ,platelates degranulation play major role
b. antibody antigen complex
c. circulating complex

156. Which one of the following is correct
a.csf production is 500ml/day
b. hyperkalemia occurs in sever diabetes mellitus
c. 98 % potassium is present intra cellularly

157. Heparin prevent thrombus
a. propagation
b. embolization
c. formation
d. organization

158. Anti thrombin 3 is activated by
a. heparin
b. warferine
c.PAF
d.VWF

159. Which of the following organism produce hemorrhagic fever when person is infected for the 2nd time
a.CMV
b.HSV
c. dengue
d. rubella

160. Which of the following is inappropriate
a. hyperplasia is inc in number of cell
b. hypertophy is inc in size
c. hyperplasia n hypertrophy can not occur in the same tissue

161. Regarding parasympathetic stimulation
a. increase PR interval
b. decrease PR interval
c. decrease QRS interval

162. In case of hyperthyroidism, which is inappropriate
a. increase bone demineralization
b. calciuria
c. hyper phosphatemia
d. hypercalcemia
e.hyperphosphaturia

163. At alveolar level, microbicidal function is done by
a. alveolar macrophages
b. IgA
c. mucus

164. A patient has bone sarcoma, radiations were given,, after some days patient developed skin ulcer at site of radiation, which is not healing. This is most likely due to
a. endartritus obliterans
b. infection
c. malignancy
d. venous thrombosis

165. O2 n H2O2 is produced in neutrophil from
a. peroxisome
b. mitochondria
c. lysosome
d.RER
e. nucleus

166. Respiratory center in brain is sensitive to changes in
a.PCO2
b.PO2
c. pH
d. H ion concentration

167. Regarding Opiods
a. can be safely given with mono amine oxidase inhibitor
b. can be given in increased intra cranial pressure
c. older persons are less sensitive to it, so increase dose should be given

168. In which of the following vein venous PaO2 n PaCO2 is appropriate with arterial blood
a. femoral vein
b. anticubetal vein
c. intenal juglar vein
d. subclavian vein
e. veins on dorsum of a warm hand

169. External carotid artey is differentiated from internal carotid artery
a. more pulsatile
b. branches in neck
c. deep

170. A person after some kind of thermal stress, was found to be unconscious, on examination he has cold clamy extremities, core body temperature 99 F, n has hypotension,, which of the following phenonmenon occurred
a. heat exhaustion
b. heat stroke
c. hypoyhermia

171. A patient has pituitary tumor, in addition to blindness from compression of optic chiasma, it has also eroded lower part of hypo thalamus. Which of the following will result from hypothalamus lesion
a. hyperphagia
b. hyperthermia
c. hypothermia

172. Most common congenital heart disease
a. ASD
b. VSD
c. TOF
d.PDA

173. Which of the following autoimmune disease involves only single organ
a. SLE
b. RA
c. cystic fibrosis

174. EBV causes which malignancy
a. nasopharyngeal carcinoma
b. kaposi sarcoma
c. burkitt’s lymphoma

175. About chalamydia
a. cause choriorretinitis
b. cause trachoma
c. is aerobic organism
d. is club shaped

176. When loop diuretic given, which one of the following is correct
a. dec interstitium osmolality,so dilute uurine is produced
b. dec osmolality of tubular fluid
c. dec calcium in urine
d. dec urea secreted in urine

177. Central artey of retina is related to
a. superior orbital fissure
b. inferior orbital fissure
c. optic canal
d. cavernous sinus
e. facial vein

178. Turbulence in vessel is increased by increase in
a. diameter
b. velocity
c. radius
d. viscosity

179. About broncho pulmonary segment
a. supplied by tertiary bronchiole
b. is independent of each other
c. artey is anterior to bronchus
d. vein is posterior to bronchus

180. Osmlarity increase with increase in
a. number of solute particles
b. size of solute particles
c. molecular weight of solute particles

181. Blood supply of stomach
a. right gastric artery supply lesser curvature
b. right gastroepiploic artey is branch of gastrodudenal artery
c. short gastric artery is branch of hepatic artery

182. What is true regarding fibroadenoma of the breast ?
a. posterior acoustic enhancement in less than 50%
b. is likely to be tender to palpation
c. macro calcifications are usually seen
d. regresses after menopause
e. the presence of a halo is an ominous sign

183. Medullary branch of vertebral artery is damaged on right side, which of the following will result
a. loss of hypoglossal nerve function on same side
b. loss of hypoglossal function on opposite side
c. loss of all sensation on opposite side
d. loss of voluntary movement on opposite side

184. Insulin secretion is decreased by
a. glucagon secretion
b. food intake
c. somatostatin release
d. pituitary gland

185. Connective tissue in all body except head n neck, is derived from
a. ectoderm
b. endoderm
c. mesoderm
d. ecto + meso
e. meso +endo

Medicine June 2012 FCPS Part-1 Paper

1 intraembryonic coelom develop from

a )lateral plate mesoderm

b)paraxial mesoderm    

c)extraembryonic coelom

2 regarding fetal circulation

a)single umblical artery in diabetic

b) singleumblical artery in htn

c) single artery in 5 % singleton pregnancy

3 chorionic villi main component

diciduaparietalis

chorionic plates

               

4 cardiac output main determinant

a )heart rate

b) stroke volume

c) venous return

5 insulin deficiency

 a) hypokalemia

 b) metabolic alkalosis

c) increase fat mobilization from liver

6 high plasma calcium causes

a) inc 1 25 dihydrocholecalciferol

b)tetany

c)inc 24 25 dihydrocholecalciferol

7 bradycardia is not feature of

a) ivedrophonium

b) ocularmasage

c) puling of extra ocular muscles

d) local atropine

8 hypercalcemianot related to

a)hcc carcinoma

b) ovarianca

c) breastca

d)prostate ca

8 all are secondary metastatic bone tumor except

Thyroid

 breast

prostate

 liver

9 after hyperpolarization is due to increase

k

cl

na

10 qrs is prior to

ventricular systole

ventricular diastole

atrial systole

atrial diastole

11 Early asthma attack asociated with

a) inc co2 tension

 b) inc lung compliance

c) dec co2 tension

12.In summer season fasting man which is increased

a)ADH

 b) ANP

c) Insulin

d)Aldosterone

13 which inc in extracellular volume expansion

 a) ANP

 b) Angiotensin 2

c) aldosterone

14 first part of duodenum

a) related to caudate part of liver

 b) surounded by hepatoduodenal ligament

c) circular fold present internaly

15 most lethal premalignant lesion of oral cavity

 a) erythroplakia

b) leukoplakia

 c) lichenplanus

16 Oral Contraceptive Pills  increase risk of

a) thromboembolisim

b) breastca

 c) endometrialca

17 most common cause of subacute endocarditis

staphylococcus

streptococci viridian

enterococci

18 growth factor receptor present on

a) nucleus

 b) plasma membrane

19 in activated toxin used as toxoid vaccine in

 a) measles

b) mumps

 c) tetanus

20 adult polycystic kidney associated with

 a) X- linked

 b) Autosomal Dominant

c) Autosomal Recessive

21 diagnosis of typhoid during 2nd week by

 a) blood culture and widal

 b) blood culture

 c) widal

22 50 yr old male presented with abdominal pain raised serum amylase. Omentum shows

a)gangrenous necrosis

b) fat necrosis

23 diagnostic feature of plasamodiumfalipirum

a)black water fever

b)malaria

c)DIC

24 granulamatousinflamation w/o caseous least likely cause is

 a) sarcoidosis

 b) leprosy

 c) tuberclosis

25 50 yr old male present with severe abdominal pain raised amylase omentumshow

a) fat necrosis

b) granulomatousinflamation

26 which vitamin used as coenzyme in faty acid synthesis

a.biotin

b.vit B6

c.vit c

27 which of following harmone act as steroid harmone on its target tissue

thyroid

Parathyroid 

adh

28 regarding immunoglobulin which is true

 a) incomplete form excreted in urine

 b) arelipoprotien

c) are secreted in milk as Ig E

d have two heavy chain which are non specific

29 metabolisim of brain

 a) take free fatty acid from blood

 b) contain large stores of glycogen

 c) 20 % o2 consumption at rest

30 regarding glycolysis most apropiate

 a) pyruvate is end product of aerobic and lactate of anaerobic

 b) reversible process

31 )pituarity lies posterio superior to

a)frontal sinus

 b) ethmoidal sinus

 c) sphenoid sinus

32 simple squamous epithelium lies

a) pct

 b) dct

c) neck of nephron at urinary pole

d collecting duct

e)loop of henle

33 fibrocartilage

a) intervertebral discs

b) epiglottis

 c) laryngeal cartilage

34 regarding thyroid

a)parathyroid lies anteri posterior

b) epithelium changes shape according to function

 c) collecting ducts are present in gland epithelium

35 spinal cord

a) in new born conusmedularis end at L3

b)posterior median sulcus deeper than anterior

 c) filumterminlum attach at s2

d) spinal nerve form 2 cm beyond intervertebral faramina .

36 autsomal dominant

a) affected person are usually heterozygotes

b) clinicallyalwaz expressed in pt containing mutated gene

 c) unaffected children v 50 % chance of transmission of gene from affected parent

37 atypical lymphocytosis doesnot occur in

a)congenitalsyphillis

b) whooping cough

 c) burkitt lymphoma

c) infectious mononucleosis

d) walderstormmacroglobulimia

38 dialysis fluid differ from plasma

 a) contain less calcium than plasma

 b) contain more pottasium than plasma

 c) contain more glucose than plasma

39 antibody produced by

 a) plasma cells

b)eosinophills

 c) monocytes

40 isoniazid induced peripheral neuropathy prevented by

a) Vit B1

b) Vit B6

c)Vit B12

 d) Niacin

41 which type of collagen increase strength in wound healing

a) type 1

 b) type 2

c) type 3

d)type 4

42 in stage of starvation which type of sequence is correct

carbohydrate-fat-protein

carbohydrate-protein-fat

fat-carbohydrate-protein

d protein-fat-carbohydrate

43 straberryhemangioma

a) occur in pregnancy and cirrhosis

b) regress spontaneously by 5 yr

 c) most commonly in lt atrium

 d) bypolyvinychloride

44 clostridumtetani

may occur weeks to months after innoculation

g +ve aerobic

secrete exotoxin

45 ligamentumarteriosum connect

a) left pulmonary artery with arch of aorta

b)pulmonary trunk with arch of aorta

46 regarding SLE all are correct except

a)ANA +ve

 b) HLA b27 present

c )glomerulonephritis is most common cause of death

47 Neural tissue derived from

a)ectoderm

b )ectoderm+mesoderm

c)ectoderm+endoderm

48 which of following pituarityharmone inhibited by hypothalamus

a) growthharmone

b) prolactin

50 true epithelium not found in

a) blood vessel

b)thyroid

c)intraarticular space of joints

d)body cavities

51 during pregnancy fetus v chance of developing renal agensis and oligohydraminos which is responsible

a) captopril

b) spirononlactone

52 in gas gangrene death is due to

A toxemic shock

54 which one of folowing is malignant tumor

a)chondroma

b) glioma

 c) pseudolymphoma

d)meningioma

 55 patient with loss of little finger sensation after posterior dislocation of elbow joint what is most likely injured

flexor collaterall ligament

ulnar collateral ligament

radial collateral ligament

 56 About scalp most inapropiate

a)resist infection transmission

b)vessels in superficial fascia

57 stab wound at supraclavicular region causes lesion of axillary musculcutaneous long thoracic nerves which one of following is invovled

a)C4

b C6

 cT1

58 prehepatic blood flow obstruction ocurrsin all except

a)buddchiari

 b) pleural effusion

c polycythemia rubravera

59 bilateral loss of all sensation occur in

 a) complete transection of spinal cord

60 regarding venous pulse all are except

a)v wave due to venous retuurn

b)a wave due to atrial diastole

61 splenic infarction comonly occur in

a) ITP

b) CML

c)hypersplenisim

62 in which of folowingdec arterial o2 saturatio w/o dec arterial o2 tension

a) anemia

b) low v/q

 c) carbon monoxide poisning

63 female lady with recurrent rashes on thigh abdomen and limbs after taking sea food which of following is responsible for it

a)delayed cell type

 b) localized anaphylaxis

c)immune complex mediated

64 protein canot cross glomeruli because

a) -ve charge of proteoglycans on basement membrane

b)fenestrated endothelium

65 ligamentumarteriosum connect

 a) left pulmonary artey with arch of aorta

 b) pulmonary trunk with arch of aorta

66 regarding sle all are correct except

a) ANA +ve

b) HLA b27 +ve

 c) glomerulonephritis is most common

67.BMR mainly increased by

a)thyroxine

 b) pregnancy

c) excercise

d) stress

e)phenobarbital

68 cerebellum

a) connectedto medulla thru middle cerebellar peduncle

b)cordination

c)lies below tentorium cerebelli

69 mysthania gravis which antibody present

igG

ig M

70 10 yr old child with achilles tendon xanthoma blood cholestrol 820mg folowing is most likely case

a)HDL receptor defeciency

b) LDL receptor defeciency

71 all of following cause sinusoidal portal hypertension except

a)alcoholisim

b) fatty liver

 c) ch active hepatitis

d) schistosomiasis

72 theraupeticdose can be measured by

a) plasma half life

 b) potency

c)efficacy

73 warfarin dose adjusted with

a)cimetidine

b)isoniazid

74 drug contraindicated in CLD

a) lorazepam

 b) paracetamol

c)pentazocine

75 EBV causes burkitt lymphoma which is appropriate

a)affectdna repair

b) producedna toxin

 c) cause mitochondria injury

 d) everyafricanburkittlymphomapt transmit ebv genome

 e) everypt of burkitt lymphoma v antibodies against viral capsid antigen

76 CCK gastrin most apropiate

a)5homology aminoacids

 b) same five terminal aminoacids(t)

77 gastrin main function

a)stimulate GIT motility

b)inchcl and pepsin secretion

78 which of folowing is not GIT hormone

a) guanylin

b)neurotensin

c) melatonin

d) substance p

 e) motilin

79 renal main compensation in respiratory alkalosis

a)dec production of ammonia

b increase NaHCO3 secretion

80 RBCs osmotic fragility most apropiate

a)some drugs causes lysis

b)swell up in hypotonic

c)shrink in hypertonic

 d) complete destruction of rbc in 0.35 %nacl

e in membrane defect of rbcs

81 corpus striatum

a)amagdyloid + lentiform

b) caudate +putamen

 c) caudate + globuspelidus

 d) amagdyloid + globuspallidus

82 in mucosal changes in chronic rhinitis which cell increase

a)mast cells

 b) lymphocytes

c) goblet cells

 d) basophils

83 17-ketosteroids

a)include testosterone

b) index of adrenal androgen

84 pt on TPN most common complication

hyperglycemia

hyponatremia

hyperkalemia

85 main potent chemotactic agent

c3a

c5a

86 i/m morphine

a ) independent of blood flow

b) stable in slow release

c) pain relief in 3 -4 hr

d peak little variable

 e) onset in  108 min

87 falciform ligament contain

 a) triangular ligament

b) round (teres )ligament

88 pt v difficulty in comprehension and intellectual brain function which brain area affected

a) brocas

b) wernicks

89 maximum ventricular filling occur during

 a) isovolumetric relaxation

b) atrial systole

c) rapid inflow

d)diastasis

90 sweat gland

a) numerous on back as compare to palm

b) innervated by sympathetic

91 which of following is important mediator of inflamation

a) complement system

b)opsonin

92 which of folowing not carcinogen

a)bacterial product

 b) pollution

c) viruses

93about  lung

a)pulmonary artery o2 saturation 75 %

b) rt ventricular pressure 25 / 10

c) pulmonary artery pressure 10mmhg less than rt ventricular systole..

94 irritant receptors in airways

a)present near epithelium

b) stimulated by stretching

c)causes coughing and broncoconstriction

d)rapidly adapting

95 in inc airway reesistance

a)inc in residual volume

96 sympathetic stimulation causes

a)bronchodilation

b)vasodilation in skin

97 65 yr old women complaints of dry eyes which ganglion damaged

a) pteregopalatine

b) otic ganglion

c) ciliary ganglion

98 posterior triangle of neck

a)contain posterior rami of C 2,3,4

b) trapezius form floor

c) roof formed by investing layer of deep cervical fascia

99 lung bronchopulmonary segment

seperrate arterial supply

directlyy connected with each other

100 content of posterior mediastinum

a) trachea

 b) Superior Vena Cava

 c) descending thoracic aorta

101 fooreign body in superior lobar bronchus which of following lobe collapsed

a)apical superior

b)superior basal

102 secondrycartilagenous joint

 a) maniburosternal

b) costochondral

103 HLAgene present on chromosome number

a)4

b) 6

104 Rightsuprerenal vein drain into

a)rt renal vein

b) inferior vena cava

105 regarding anus

a)supplied by superior and inferior rectal vein

b inferior mesentric drain into portal vein .

106 juglodigastric lymph node drain

a)palatine tonsil and tongue

107 detoxification of drug occur in

a)mitochondria

b) SER

c) RER

108 fibrous and parietal pericardium suplied by

a)phrenic nerve

 b) intercostal nerve

109 azygousvein

a) in venography to visualize dye injected into ascending thoracic

 b) posterior to abdominal aorta

c) arise form right renal vein

d)arise from lt renal

e) pass via T8 diaphragmatic opening

110 kidney most inappropiate

a) reciecve 10 % of cardiac output

b)cortex richly vascularized than medulla

111 complete common peroneal nerve lesion result in complete loss of

a) dorsiflexion of foot

 b) eversion of foot

 c) inversion of foot

 d) sensory loss of dorsum of foot

112 person lie uncovered in room heat loss via

a) conduction

 b) radiation

c) convection

113 axillary block done but lateral forearm sensation spared which of following nerve not blocked

a) axillary

b) musculocutaneous

114 dimnished jaw jerk due to lesion of

a) mesencephalic nucleus of trigeminal

b) facial motor nucleus

115)mast cell beneath epithelium

 a) contain granule in cytoplasm

b)resemble eosinophil in function

 c) release histamine and heparin

d contain IgA on surface

 116) epiphyseal plate

 a) contain mature collagen

 b) increase in length of bone in adolescent

 c) elastic cartilage

117)DIC most inapropiate

a) widesspreadmicrovascular thrombi

b) fibrin degradation products low levels

c)may be treated by heparin

 118) left ventricular failure

a) inc pulmonary capillary pressure

 b) orthopnea when standing

119 most sensitive growth hormone test

a) arginine infusion test

 b) insulin tolerance test

 c) excercise tolerance test

120 damaged endothelium exposed collagen activate clottting via

xII

vIII

vII

121 light enter into one eye

a)constrict pupil and dilate opposite

b)no change in size of pupil whose muscuranic receptor blocked by atropine

122 basilar artery and Internal carotid artery comunicate by

posterior comunicatingartery

posterior cerebellar artery

canterior communicating artery

123 right optic nerve lesion

alt homonymous homonopia

b) rt homonymous homonopia..

124 left optic nerve lesion?

a)rt homonymous heminopia

 b) lt homonymous heminopia

125 all are parasympathetic cranial nerve except

a)III

b v

cvII

127 REM sleep

 a) beta wave predominate

 b) sleep walking

c) canot recall dream

128 Cranial nerve emerge from pons

motor fibre from v vI VII

 CN VII

 CN III IV

 129 cervical dysplasia caused by

a) IUCD

b)HPV

130 during excercice coronary blood flow maintained by

 a) sympathetic stimulation

 b) local metabolites

131 ECF and ICF difference

a) ECF contain high Na Ca (t )

b)ICF contain high Na low K

132 during intravascular hemolysis hb bind to

a)hepatoglobin

b) albumin

133 pt suffering from severe diarheoa

a)dec k content of body

b) decna content of body

134 middle aged old male taking betel nuts and pan he z most likely to develop

a) submucous fibrosis

b)erythroplakia

c)leukoplakia

d)keratinization

135 which of folowingdec gastric empting

a) Alcohol

 b) Mg sulfate

caluminium sulfate

136 investigation of choice in diabetic nephropathy

a) urine albumin

137 basic drug binds to

a)Alphaglycoprotien

b) albumin

138 cavernous sinus

oculomotor trochlear and opthlmic present in lateral wall..

connected posteriorly to facial vein

drain directly into straight sinus

139 greatest pressure drop in arteriole because

a) highest resistance in arterioles

140 nicotinic ach receptor

a) numerous in cns

b) blocked by curare

141 most serious effect of diptheria toxin is on

a) larynx

 b) pharnx

c)heart

142 regarding tubocurarine

a) causus ganglionic blockade

143 ideal physician

a)good bed side skill manner

b) good medical knowledge

 c) integrated regular....

144 pt doctor relationship

a) active listening

145 5 yr child with generalized edema and protienuria of 3.6 gm in 24 hr the most important underlying mechanism of edema

 a) increased hydrostatic pressure

b) dec colloid osmotic pressure

146 left hemidisection of spinal cord which of folowingnot be present on ipsilateral side

a) loss of vibration

b)loss of pain

c) loss of two point discrimination

147 external juglar vein most likely

a) begin on surface of sternocliedomastoid behind angle of mandible

b) terminate by piercind deep cervical fascia

148 a pt with diabetic kadidnot respond to treatment and died autopsy show inflamatory lesion in kidney brain and lung with some fungus most likely organism

a)mucor mycosis

149 35 yr old female diagnosed to with PAN 2 yr back present with bp 220/120 ch feature confirming diagnosis

a) fibrinoid necrosis of arterioles

150 26 yr old women present at 36 week of gestation with bilirubin 30 mmol /l most life threatning hepatitis to mother in near future would be

a) hepatitis c

b) hepatitis b

 c) hepatitis e

151) on which of following hypothalamus have inhibitor effect..

a>prolactin

b>gh>

 c >acth

152)most specific test for growth harmone excess

a> arginine

b>excercise tolerance tese

c> insulin tolerance test

153 )primary auditory cortex lies in which lobe?

occipital

superior temporal

inferior temporal

154 regarding hypercalcemia what will happen

a>calcitonin decrease

b> 1 ,25 oh vitd incresae

24 25 oh increase

tetany

155 blood pressure in capillaries decrease because

they have  highest cross sectional area

..other i dnt remember..

156 folowing not decrease blood pressure..

.a> press eye    

b>press extraocular muscle

c>giving atropine

157 one question was regarding strawberyhemangioma

mostcomomn site in left atrium

regress by 5 year

158 regarding broncho pulmonary segment

each v independent blood supply

 b>are connected indirectly

159 rt apical segmental bronchi suply

a>rt superior apical

160) O2 saturation decrease and o2 tensin high in

 a> anemia

co poisning

hypoventilaton

161) difference between alveolar to arterial po2 donot change in

a>congrt to lt shunt

b>atelectasis

hypoventilation

d>

162)decrease in blood po2 type of hyoxemia

a> hypoxia

 163 regardin left venticular failure

pulmonary capillaries congestion occur

b> orthopnea on standing

 164 in posterior fracture to elbow of child loss of sensation on little fingre v occured which ligament / tendon ruptured

ulnar collateral

 radial collateral

flexor carpi ulnaris tendon

 165 regarding posterior triangle of neck

 a>trpezius form floor

 b >sternocliedomastoid lie posteriorly

c>deep cervical fascia cover it

d>containts posterior rami of c2c3 c4

166)scenario of bilary colic pain drug given in adjuvant to morphine

a>pethidine

 b>hyosine

167 pethidine when given iv l cause

mi depression

tachcardia

halulcination

dysphoria..

delirium

168 morphine when given intramuscularly

duration of action 3 -4 hr

 onset 0f action 104 min

 sustained release

169 ccfpt with crepitations came first time drug  given

a> furosemide

170 corpus striatum conssist of

a> putamen + caudate

171 hla on which chromosome

 a>4

b> 6

171)a female pregnant have cat as a pet what infection can occur in child

 a> toxoplasmosis

172)intaembryonic coelom develop from

axial mesoderm

lateral plate mesoderm

paraxial mesoderm

extraembryonic mesoderm

173)cardiac output depends on

stoke volume

heart rate

venous return

174) end diastolic volume depend upon

a> venous return

 b >distensibilty of heart

 c> duration of diastole

175 a 5 yr child developed proteinuria >3 g / dl and developed edema cause of edema l be a> decreased oncotic pressure

176 a girl developed uritcariarashe at arm yrunk leg and face after ating sea food what l be the cause of it

localized tpe 1

b generalized type 2 hypersensitivity

177 symptoms of mysthania gravis were given like then was question which is pathology

antigen a

complex are formed ..

178which is secondrycartilagenous joint

sternoclavicular

 b> between 1st rib and sternum

c> between maniburum and sternum

179fibrocartilage

larynx

  trachea

 between vertebrae

180standard deviation is used to

a> measure sample size

181juglodigastric lymph node drain

a> palatine tonsil and tongue.

182)whichdoesnot contain true epithelium

 a> vessels

serous cavities

joint cavities

183) main function of gastrin

a>inc gastrointestinal motility

b>inc acid pepsin secretion

184gatrin and cck

a v same 1st 90 aa

b>v same 5 terminal 5 carboxl terminal

185 which antacid delays gastric emptying (wrong question)

alcohol

sodabicarb

186 kidney compensate for alkalosis by

dec H2 production

 in NaHCO3 secretion

187)regarding cerebral metabolisim

a> consume 20 percent of o2

188)regarding kidney which is false

a> 10 percent blood flow..

189)symptoms of acute rhinitis which cell responsible

a> mast cells

190) primary phagocytic

 a> neutrophils

b> macrophage

191) chronic rhinitis cell present in nodule

 a> lymphocyte

b>goblet cells

macrophage

c> mast cell

192 regarding kidney glomerular filtrate is

 a>ultrafiltrate

193 protein donot pass thru kidney because

 a> -ve charge in basement membrane and mesangium

194)basic drug bind to

a>glycoprotien

195most malignant lesion of oral cavity

a>erytoplakia

196 heat loss when person sitting nude

 a> convection

197.which of following is major circulating phagocyte??

a.macrophage

b.neutrophil(correct)

c.monocyte

d.mast cell

e.dendritic cell

Paper II

1.cause of spleen infarct??

a.ITP

b.idiopathic thrombocytosis

c.CML(correct)

d.hyperspleenism

e.

2.which of following is major circulating phagocyte??

a.macrophage

b.neutrophil(correct)

c.monocyte

d.mast cell

e.dendritic cell

3.about single umbilical artery which is correct??

a.due to hypertension in pregnancy

b.normal in 5%

c.associated with maternal diabetes(correct)

d.

e.

4.organ least likely to b affected if blood supply blocked??

a.intestine

b.liver(correct)

c.pancreas

d.kidney

e.spleen

5.scenario on pregnant lady having cats in home…..??

a.toxoplasmosis(correct)

b.leshminiasis

c.EBV

d.cytomegalovirus

e.HIV

6.which of following vitamin is cofactor for fatty acid oxidation??

a.cobalamin

b.biotin(correct)

c.vitamin A

d.niacin

e.vitamin D

7.which is malignant tumor??

a.meningioma

b.chordoma

c.glioma(correct)

d.hydatiform mole

e.hamartoma

8.peripheral neuropathy due to INH treated with??

a.vitamin B12

b.vitamin B1

c.vitaminB6(correct)

d.vitamin A

e.vitamin E

9.diagnosis of typhoid in 2nd week by??

a.blood culture

b.widal test

c.bloodculture+widal test(correct)

d.urine culture

e.

 10.most serious side effect of diptheria toxin is on??

a.nerve

b.heart(correct)

c.

d.

e.

 11.which hormone act by steroid hormone mechanism??

a.prolactin

b.epinephrine

c.growth hormone

d.thyroid hormone(correct)

e.

 12.growth factor receptors r present on??

a.nucleus

b.cytosol

c.cell membrane(correct)

d.nuclear membrane

e.

 13.drug detoxification occurs in??

a.mitochondria

b.rough endoplasmic reticulum

c.smooth endoplasmic reticulum(correct)

d.peroxisomes

e.

 14.patient taking anti tuberculous drugs, cause of color blindness??

a.rifampicine

b.ethambutol(correct)

c.pyrazinamide

d.INH

e.streptomycin

 15.scenario on non caseating granuloma occurs in??

a.tuberculosis

b.leporsy

c.sarcoidosis(correct)

d.amoeboma

e.

‎16.one of following is not occur in shock??

a.tachycardia

b.decrease cardiac output

c.increase urine output(correct)

d.muscle weakness

e.

 17.during starvation which pattern of fuel consumption occur??

a.protein˃carbohydrate˃fatty acid

b.fattyacid˃protein˃carbohydrate

c.carbohydrate˃fattyacid˃protein(correct)

d.

e.

 18.cells increase in allergic condition??

a.basophils

b.neutrophils

c.mast cells(correct)

d.monocytes

e.macrophages

 19.antacid which delay gastric emptying??

a.magnesium hydroxide

b.sodium bicarbonate

c.aluminium hydroxide(correct)

d.magnesium carbonate

e.

 20.which of followin doesn’t cause hypercalcemia??

a.breast carcinoma

b.hepatocellular carcinoma

c.bronchogenic carcinoma

d.ovarian carcinoma

e.prostate carcinoma(correct)

 21.HLA gene present on??

 a.chromosome4

 b.chromosome7

 c.chromosome9

d.chromosome6(correct)

 e.chromosome3

 22.scenario in which patient is having loss of accomodation,which area involved??

a.pons

b.medulla

c.midbrain(correct)

d.cortex

e.

 23.organism of subacute endocarditis??

a.S.aureus

b.S.viridans(corrrect)

c.S.bovis

d.

e.

 24.haemoglobin bind to??

a.albumin

b.hepatoglobin(correct)

c.globulin

d.

e.

 25.scenario on volume expansion,which hormone increases??

a.aldosterone

 b.angiotensin1

c.ANP(correct)

d.renin

e.

 26.in chronic rhinitis which cells increases??

a.basophils

b.goblet cells(correct)

c.IgE

d.

e.

 27.juglodigastric lymph nodes drain??

a.palate

b.tongueand palatine tonsils(correct)

c.

d.

e.

 28.falciform ligament contains??

a.triangular ligament

b.round ligament(correct)

c.coronary ligament

d.

e.

 29.defect in language comprehension and intelligence??

a.frontal cortex

b.brocas area

c.wernicks area(correct)

d.

e.

 30.about cerebellum??

a.lies below tentorium cerebeli(correct)

b.connected by superior peduncles to pons

c.

d.

e.

‎31.which of following is potent chemotactic factor??

a.IL-1

 b.C3a

c.C5a(correct)

d.arachidonic acid

e.IL-8

 32.erythropoietin is secreted from??

a.maculadensa

b.peritubular interstitial cells(correct)

c.hepatocytes

d.

e.

 33.patient with posterior dislocation of elbow is having pain and numbness in little finger,which ligament or tendon damaged??

a.flexor carpi ulnaris

b.annular ligament

c.ulnar collateral ligament(correct)

d.radial collateral ligament

e.

 34.one of following is feature of acute tubular necrosis??

a.concentrated urine

b.oliguria

c.hyperkalemia(correct)

d.proteinuria

e.

 35.corpus striatum includes??

a.amygdala+caudate

b.amygdala+caudate+putamen

c.amygdala+putamen

d.caudate+putamen(correct)

e.caudate+globuspallidus

 36.which of following correct regarding brain??

a.needs glycogen

b.consume 20% oxygen at rest(correct)

c.

d.

e.

 37.drug contraindicated in CLD??

a.pentazocine

b.lorazepam

c.acetaminophen

d.hyosine

e.

 38.all of following form anterior relation of kidney except??

a.spleen

b.pancreas

c.diaphragm(correct)

d.

e.

 39.which artery connects basilar artery to internal carotid artery??

a.anterior cerebral artery

b.anterior communicating artery

c.middle cerebral artery

d.posterior communicating artery

e.inferior cerebellar artery

 40.true about sweat gland??

a.supplied by sympathetic cholinergic(correct)

b.

c.

d.

e.

 41.ifdorsalispedis artery is absent congenitally,which artery will supply area??

a.plantar arch

b.peroneal artery

c.medial planter artery(correct)

d.lateral planter artery

e.first metatarsal artery

 42.person chews bettlenuts,its associated with??

a.lichenplanus

b.lukoplakia

c.submucosal fibrosis(correct)

d.erythroplakia

e.

 43.patient having hypertension 210/120 ndcreatinine 7,defect is in??

a.maculadensa

b.JG apparatus(correct)

c.renal tubules

d.

e.

 44.intraembryoniccelom is formed by??

a.extraembryoniccelom

b.lateral plate mesoderm(correct)

c.

d.

e.

 45.which is correct regarding strawberry haemangioma??

a.regress within 5 years of age(correct)

b.

c.

d.

e.