1. Resistance varies indirect proportional to ?
a. Viscosity
b. Hematocrit
c.length of the vessel
d. radius of the vessel
e. velocity of the blood
Answer is = D
2.The difference of osmolarity between interstitial fluid and plasma is ?
a.1 mosm/l
b.2.5 mosm/l
c. 3 mosm/l
d. 5 mosm/l
e. No difference
Answer is = 1 mosm/l
3.Which of the following cranial nerves are parasympathetic ?
a. 3,4,7,10
b.3 ,7,9,10
c.2,3,6,7
d. 1 ,2 ,5,10
Answer is = b
4.Regarding QRS complex,what is inappropriate ?
a.Occurs due to ventricular depolarization
b.has +ve and -ve waves
c.Occurs just before ventricular systole.
d. Indicates atrial depolarization
Answer is = D
5.65% of filtered Na is reabsorbed from
a.PCT
b.DCT
c.loop of henle.
d.Collecting duct
Answer is a
6.Venous return depends upon ?
a.velocity of the blood
b.increased mean systemic filling pressure
c.cardiac output
d.stiffness of vessel
Answer is B
7.Volume remaining in the lungs after tidal volume expiration is ?
a.residual volume
b.expiratory reserve volume
c.FRC
d.vital capacity
e.TLC
Answers is C
8. Regarding thorax,find out the wrong statement
a.pump handle increases transverse diameter
b.abdominal type of respiration is seen in children
c.diaphragm is important muscle for respiration
d. xiphisternum is located at T 9 vertebrae.
Answer is B
9. In asthmatic patient allergen react directly with ?
a. mast cells
b. eosinophills
c.macrophages
d. epithelial cells
Answer is A
10. PTH increases CA re-absorption by acting on ?
a.pct
b. dct
c. loop of henle
d. collecting duct
Answer is B
11. Oxygen HB-dissociation curve shifts to the left due to ?
a. increased CO2
b. decreased PH
c. high altitude
d. carbon monoxide poisoning.
Answer is D
12. Elimination of aminoglycosides antibiotics from the body in elderly is decreased due to decreased ?
a. fat metabolism
b. hepatic metabolism
c. renal excretion
d.plasma protein binding
e. volume of distribution
Answer is C
13.Immune mediated disorders occur due to location of genes on ?
a.spleen
b.rbc
c.wbc
d.liver
e.kidney
Answer is C
14. Gastric emptying is decreased by
a.gastrin
b.CCK
c.secretin
d.GIP
Answer is B
15. Patient presented in ER with dyspnea ; Ph = 7.13 , Co2 = 55 mm hg , HCO3 = 26 mmol/l , Po2 = 49 mm hg ; He is K/C of COPD , what is the most likely diagnosis ?
a. Respiratory acidosis
b. respiratory alkalosis
c.respiratory acidosis with type 1 respiratory failure
d. fully compensated respiratory acidosis
e.respiratory acidosis with type-2 respiratory failure
Answer is E
16. Hamartoma is defined as ?
a.mass of mature disorganized tissue indigenous to that organ
b. ectopic rest of normal tissue
c. a tumor that can metastasize
d. a malignat tumor that can cause serious complications
Answer is A
17. The cutting of pituitary stalk will predominately lead to increased levels of which pituitary hormone ?
a. GH
b. prolactin
c. TSH
d. ACTH
e. FSH and LH
Answer is B
18. L- DOPA given in the treatment of parkinson's disease leads to decrease in levels of which hormone ?
a. Prolactin
b. GH
c. Cortisol
d. testosterone
Answer is A
!9. In the presence of ADH, the water is maximally reabsorbed from ?
a. PCT
b. cortical collecting tubule
c.medullary collecting duct
d. loop of henle
e. early distal tubule
Answer is A
20. Strong chemotactic agent is
a. C5a
b. C5b
c. C3b
d. opsonin
e. platelet
Answer is A
21. Carcinoma stains with which of the following ?
a. desmin
b. keratin
c. vimentin
d. pas
e. congo red
Answer is B
22. Which of the following malignancy is transmitted as autosomal dominant mode of inheritance ?
a. ca-calon
b. retinoblastoma
c. ca-breast
d. ca-live
Answer is B
23. A lady is having cervical lymph adenopathy and is diagnosed as a case of lymphoma, which immunological disorder she is most likely having ?
a. aids
b. sle
c. pan
d. ra
e. sjogren syndrome
Answer is A
24. First symptom that occurs due to hypopituitarism due to pituitary tumor would be ?
a. hypothyroidisn
b. hypogonadism
c. hypoglycemia
d. hypoadrenalism
e. hypovolumia
Answer is B
25. Which of the following is benign tumor ?
a. adenoma
b. hepatoma
c. melanoma
d. lymphoma
Answer is A
26. Which of the following has least malignant potential ?
a. fap
b. metaplastic polyp
c. tubular adenoma
d. villous adenoma
Answer is C
27. Which of the following statement is "incorrect" about metaplasia ?
a. one adult cell type replaces another cell type
b. irreversible
c.can occur in lungs
d. can occur in epithelial cells
e. protective change against chronic irritation
Answer is A
28. Oxytocin and ADh originates in ?
a. neurohypophysis
b. hypothalamus
c. adenohypophysis
d.thalamus
e. mid brain
Answer is B
29. Bad news provided by doctor should be ?
a. in front of nursing staff
b. by a psychiatrist
c. at bedside
d. in front of all the family members
e. by the concerned doctor in formal session in exclusivity
Answer is E
30.Best way to start communication with patient should be ?
a. by asking cross questions
b. by asking about illness
c. by asking about name , age, address , and occupation
d. by asking leading questions
Answer c
31. Hormone which increases protein deposition in skeletal muscles ?
a. estrogen
b. testosterone
c. cortisol
d. dihydrotestosterone
e. progesterone
answer is B
32. Growth hormone ?
a. affects metabolism of carbohydrates
b. causes skeletal and cartilage growth through somatomedins
c. has half life of 6-20 mins in circulation
d. is a hormone of pituitary gland
e. is a polypeptide
Answer is B
33. Which of the following organ causes bone growth by releasing peptide ?
a. brain
b. liver.
c.kidney
d.git
e. adrenal cortex
Answer is A
34. Formation of interstitial fluid increases with decreased ?
a. capillary hydrostatic pressure
b. capillary permeability
c. interstitial fluid colloid osmotic pressure
d. lymphatic flow
e. plasma colloid osmotic pressure
Answer is E
35. The post prandial state is characterized by ?
a. high blood levels of FFA and high levels of glucagon
b. high blood levels of FFA and low levels of glucagon
c. high blood levels of glucose and high levels of insulin
d. high blood levels of glucose and low levels of insulin
e. high blood levels of insulin and glucagon
Answer is C
36 .Which of the following is inappropriate for insulin ?
a. causes entry of glucose into cells of adipose tissue
b. is anabolic hormone
c. decreases gluconeogenesis
d. causes induction of lipoprotein lipase
e. increases glycogenolysis
Answer is E
37. Correct about ANS ?
a. all sympathetic are adrenergic
b. all para - sympathetic are cholinergic
c. all sympathetic are cholinergic
d. all para sympathetic are adrenergic
e. at autonomic ganglia all are adrenergic
Answer is B
38. Which of the following has highest pH ?
a. saliva
b. pancreatic juice
c. bile
d.gastric juice
Answer B
39. A 4 year boy presented with clinical features of failure tl thrive , recurrent sinusitis , otitis media and rti . He also gives h/o chronic diarrhea, there is family h/o such complaints, the most relevant investigation in this case to confirm the dignosis is ?
a. chloride sweat test
b. fat absorption test
c. jejunal biopsy
d. vit b-12 assay
e. serum immunoglobulin level
Answer is A
40. Small child present with malabsorption , foul smelling stool , steatorrhea , deficiency of following is likely to occur in this patient ?
a. folate
b.iron
c. ca
d. vit d
e. vit b-12
Answer is D
41. Regarding active transport, find out most appropriate ?
a. occurs in few cells
b. always means Na-K pump
c. always requires glucose
d.does not require energy
e. is carrier mediated and carriers proteins are enzymatic in nature
Answer is E
42.Tractus-solitarius contains ?
a. auditory neurons
b. 1st order neurons for taste
c. 2nd order neurons for taste
d. parasympathetic fibres related to facial nerve
Answer C
43. Sharp-fast pain is mediated by which of the following fiber ?
a. c -fiber
b. a-delta
c. beta
d. theta
Answer is B
44. Regarding thalamus , most appropriate statement is ?
a. associated with behavior and emotions
b.associated with temperature regulation
c. associated with water regulation
d.plays key role in sexual funtions
e.is relay centre for all somatic and special senses
Answers is E
45. Facial nerve collects taste information from ant 2/3 of tongue through its chorda tympani branch, functional component of taste sensation is ?
a.General somatic afferent
b. general visceral afferent
c.general visceral efferent
d.special somatic afferent
e.special visceral afferent
Answer is E
46. Nerve passing through foramen ovale is ?
a.maxially
b.mandibular
c.occulomotor
d.trochlear
Answer is B
47. Patient having deviation of angle of mouth,dribbling of saliva , can not close eye and wrinkle forehead , nerve must likely involved is ?
a. facial
b. maxillary division of trigeminal nerve
c. auriculo temporal
d.mandibular division of trigeminal nerve
Answer is A
48. Hairy cell leukoplakia is associated with
a. hiv
b. fungus
c. all
d. cll
Answer is A
49. Histological characteristic of TB is ?
a. acid fast bacili
b. caseation
c.gram+ve staining
d. giant cells
Answer is B
50. Vibration is carried by ?
a. Pacinian corpuscles
b. meissners corpuscles
c.ruffini corpuscles
d.nocieptors
Answer is A
51. Static pressure is carried by ?
a. ruffini corpuscles
b. pacinian corpuscles
c.meissners corpuscles
d. nociceptors
Answer is A
52. Myxoid degeneration is mostly associated with
a. carcinoid valve disease
b.infective endocarditis
c.libman-sack's endocarditis
d.marantic endocarditis
e.mitral valve prolapse
Answer is B
53. Among st the causes of fatty changes in liver, most frequent in our country is ?
a. alcohol
b.hbv and hcv
c. halothane
d. obesity
e.starvation
Answer is B
54. Regarding dysplasia, most appropriate ?
a.disarray of cells, having loss of architecture
b.pleomorphism
c. increased mitotic figures
d. increase in size of cell
Answer is A
55. Ischemic heart disease with or with out sequel that doesn't present with characteristic clinical features ?
a. chronic ihd
b/ prinzmental angina
c.stable angina
d. unstable angina
e. mi
Answer is B
56. A young chuld on anti-malarial passed cola colored urine , what could be the cause ?
a. g6pd deficiency
b. drug reaction
c. iron deficiency anemia
d. thalessemia
Answer is A
57. Grade-4 encephalopathy is caused by ?
a. alcohol
b. paracetomol
c. ethylene glycol
d. amphetamine
Answer is B
58. A 40 year male on att for last 3 weeks c/o joint pains , his serum uric acid is raised . which is culprit drug ?
a. isoniazid
b. ethambutol
c. pyrazinamide
d. rifampicin
e. streptomycin
Answer is C
59. Drug of choice for traveler's diarrhea ?
a. aluminium hydroxide
b. dipheno-oxylate
c. metaclopromide
d. sucralfate
Answer is B
60. Angina may be worsened by ?
a. atropine
b. salbutamol
c.theophylline
d. vasopressin
e.verapamil
answer is C
61. Synapses are absent in ?
a.dorsal horn of spinal cord
b. dorsal root ganglia
c.lateral horn of spinal cord
d. sympathetic chain ganglion
e.ventral horn of spinal cord
Answer is B
62. Muscles of back are supplied by ?
a. dorsal rami of spinal nerves
b.cervical plexus
c. Ventral rami of spinal nerves
Answer is A
63. Type of join between two pubic bones ?
a. syndesmosis
b.symphysis
c.primary cartilaginous join
d. fibrous joint
answer is B
64. Most appropriate regarding fibro-cartilage ?
a. is present in nose
b. contains type 2 collagen
c. is present in intervertebral discs
Answer is C
65. Junction b/w two epithelial cells that does not allow free movement of substance is called ?
a. zona adherence
b. tight junction
c. desmosomes
d. gap junction
Answer is B
66. Patient has suffered 3rd degree burns to arm and hand , he is worried about which of the following most likely complication ?
a. wound dehiscence
b. contracture
c. keloid
d.traumatic neuroma
Answer is B
67. Regarding mid brain find out most appropriate ?
a. cerebral aqueduct forms cavity of mid brain
b. posterior surface is marked by presence of 2 colliculi
c. tectum divides into 2 crus cerebrei
d. trochlear nerve emerges from anterior surface
Answer is A
68. Which of the following receives sub-capsular afferents ?
a. lymph node
b. tonsil
c.thymus
d. spleen
e.payer's patch
69. A polymorph leukocytosis is expected in ??
a. appendicular tumor
b. glandular fever
c. mi
d. typhoid and para-typhoid
e. chronic osteomyelitis
70. Correct about respiratory zone ?
a. terminal bronchioles to alveoli
b. alveolar duct and alveolar sac
c. respiratory bronchi to alveoli
d. medium size bronchi
71. End plate fiver of neuro muscular junction contains ?
a. acetyl cholinestrase
b.pre-synaptic ach vesicle
c. post synaptic ca vesicle
d. synthesizes ach
72. Hepatic pedicle contains ?
a.hepatic vein and cbd
b. hepatic artery, hepatic vein and cbd
c.portal vein and hepatic duct
d. portal vein , cbd and hepatic artery
73. Basal ganglia complex is unique that it contains ?
a. high copper
b. low copper
c. manganese
d. high mg
74. Regarding vertebra , find out most appropriate ?
a. lumber vertebrae is heart shaped
b. C-7 has long spinous process
c. thoracic forms transverse process
d. the thoracic vertebrae is kidney shaped
75. A young lady presented with lump in outer lateral quadrant of breast which of the following group of lymph nodes is involved ?
a. anterior axillary
b. apical
c. posterior
d. internal thoracic
76. right kidney is differentiated from left kidney by ?
a. color of kidney
b. no of coverings of kidney
c. relations of structures in hilum
d. sufaces and poles in kidney
e. weight and size of kidney
78. PDA is persistent part of the left ?
a. 4th arch
b. 5th arch
c. 6th arch
d. dorsal aorta
e. ventral aorta
79. Root of the right lung is crossed by ?
a. sub clavian vein
b.arch of aorta
c.azygous vein
d. right pulmonary artey
80. Vessel which supply derivatives of foregut
a. celiac artrey
b. SMA
c. IMA
d. splenic artery
81. Following will not form the boundary of inguinal canal ?
a. lacunar ligament
b. ext.oblique aponeurosis
c. transversalis fasicia
d. conjoint tendon
e. inguinal ligament
81. Patient treated via conservative surgery for ca colon , best marker for disease progression is ?
a. alpha feto protein
b. cea
c. b-hcg
d. erythropoietin
82. Structure found 2 feet away from ileo-cecal junction at anti - mesenteric border is most likely ?
a. omphalocele
b. meckel's diverticulum
c. volvulus
d.gastochisis
e. intussusceptions
83
Monday 8 July 2013
Medicine March 2012 FCPS Part-1 Paper
1. Tumor spread by:
a. Migration of tumor cells
b. Breakdown of e-cadherin
c. sepeation of tumor cells from one another
d. Damaging extracellular matrix
e.
2. What is most common cause of congenital hypothyroidism:
a. Maternal iodide deficiency
b. Inborn error of metabolism
c. Defective embryogenesis
d. Antibodies against thyroid hormone crossing placenta
e.
3. Diabetic pat taking oral hypoglycemic drugs complain of abdominal fullness, which drug can b given to decrease gastropresis
a. Omeprazol
b. Cimetidine
c. Antacids
d. Metclopramide
e.
4. On motor bike accident fracture of neck of humerus n can,t abduct his arm.due to
a. Axillary nerve
b. Long thoracic nerve
c. Musculocutaneous nerve
d.
e.
5. Regarding trachea
a. Gap in the C shape cartilages are lying anteriorly
b. 15 cm in length
c. Recurrent laryngeal nerve pases anteriorly
d. Isthmus of thyroid lying in front of 4rt or 5th tracheal ring
e. Starts at the lower border of cricoid cartilage
6. Release of acid from stomach is mediated through
a. H1 receptor
b. H2 receptor
c. food in stomach
d.
e.
7. Diaphragm is supplied by
a. C3
b. C3,4,5
c. C4,5
d. C4,5,6
e.
8. A female at 36weeks gestation cmwith bili;20mg/dl raised SGPT & SGOT.she has returned from remote village. What can b the cause of infection?
a. HAV
b. HBV
c. HCV
d. HEV
e.
9. What is the structure arches around the root of left lung
a. Azygus vein
b. Arch of aorta
c. Left phrenic nerve
d. Left vagus nerve
e. Left recurrent laryngeal nerve
10. Regarding ESR decreased by increase in which of the following
a. Increase plasma globulin
b. Increase fibrinogen
c. Increase plasma Albumin
d. Increase globulin and albumin ratio
e. Temperature
11. Best example of pharmaco kinetics drug drug interaction:
a. Iincrease action of procain by epinephrine
b. Increase action of........... by Calcium
c. Toxicity of lithium with thiazide diuretics
d. Reverse the action of aspirin by NaHCO3
e. Reverse the action of Morphine by Naloxone
12. Following veins drain into coronay sinus, which vein continues as coronary sinus
a. Middle cardiac vein
b. Great cardiac vein
c. Anterior cardiac vein
d. Oblique vein
e.
13. Notochord arises from
a. Ectoderm
b. Mesoderm
c. Endoderm
d.
e.
14. Thyroid is derived from
a. Ectoderm
b. Mesoderm
c. Endoderm
d.
e.
15. Which one of the following is a chemical carcinogen
a. Alpha 1 antitrypsin
b. Benzidine
c. Ethyl alcohol
d. Propyl alcohol
e.
16. Contractile unit in skeletal muscle is between
a. h discs
b. z lines
c. t tubules
d.
e.
17. A/P radiograph of chest which structure forms right border of heart
a. SVC
b. IVC
c. Right ventricle
d. Arch of aorta
e. Left Atrium
18. 60 percent of work of breathing
a. is to overcome elastic recoil of lungs
b. Counteract chest wall compliance
c. Resistance offered by small size bronchi
d. Resistance by large bronchi
e.
19. Regarding nerve supply to skeletal muscle contains
a. 60%motor 40%sensory fibers
b. 40%motor 60%sensory
c. 60%motor 40%sensory and few postganglionic sympathetic fibers
d.
e.
20. Thirst stimulated by
a. ECF volume depletion
b. ICF volume depletion
c. Salt depletion
d.
e.
21. Regeneration least effected by
a. Diabetes
b. Infection
c. Uv light
d. corticosteroid
e.
22. In downs syndrome at 40 years of age
a. Alzhiemers disease
b. Stroke due to essential hypertension
c. Upper motor neuron lesion
d. Lower motor neuron lesion
e.
23. Primary cartilaginous joint
a. Costochondral
b. Teeth and jaw
c. Inferior tibiofibular joint
d. Symphysis Pubis
e.
24. Epinephrine reuptake by
a. Diffusion and reuptake
b. Diffusion, reuptake and enzyme catalysis
c. Diffusion
d. Reuptake
e. Enzyme catalysis
25. 2 yr old child presented with anemia and has hyper segmented neutrophil, MCV raised, how will you confirm your diagnosis
a. Intrinsic factor antibodies
b. Vit b12 level
c. Transcobalamin
d.
e.
26. Thrombus formation triad
a. Endothelial damage, slow blood flow, altered blood constituents
b. Endothelial damage; high blood flow, fibrin
c. Endo damage eddy blood flow
d. Plasma high blood flow
e.
27. After 6 hours of myocardial infarction which enzyme level most raised
a. CPK
b. LDH
c. ALT
d. AST
e. ALKALINE PHOSPHATASE
28. In adult female breast atrophy is commonly due to decrease
a. Estrogen
b. Estrogen and progesterone
c. Progesterone
d. Prolactin
e.
29. Patient taking MAO inhibitors, taking which of the following could cause hypertensive crisis?
a. Coffee
b. Chocolate
c. Cola
d. Pine apple
e. String beans
30. Left kidney is not related anteriorly to which of the following structures?
a. Diaphragm
b. Stomach
c. Pancrease
d. Spleen and splenic vessels
e. Splenic flexure of transverse colon
31. A 30 year man participated in marathon race the most common hormone changes you will find
a. Low Insulin, High Glucagon
b. Low Insulin, Low Glucagon
c. High Insulin, High Glucagon
d. High Insulin, Low Glucagon
e.
32. 2x2 table in biostats?
a. T-Test
b. Chi Square Test
c.
d.
e.
33. Which of the following lymphoid structure does NOT contain lymph nodules:
a. Spleen
b. Lymph node
c. Thymus
d. Payer's patches
e. Tonsils
34. A person has pH 7.48, CO2 66 and HCO3 27 . What is the diagnosis
a. Acute respiratory acidosis
b. Acute metabolic acidosis
c. Partially compensated respiratory acidosis
d. Partially compensated metabolic acidosis
e. Partially compensated metabolic alkalosis
35. A patient suffers from appendicitis. Peripheral blood shows leukocytosis. Pain will be mediated by
a. IL 1 and TNF alpha
b. Bradykinin and prostaglandin E
c. Serotonin
d. IL 6
e. enkephalin
36. In myocardial infarction, which earliest change occurs in formation of aschoff bodies
a. Fibrinoid necrosis
b. Inflamaton
c. Giant cell
d. Eosinophilia
e.
37. Regarding movements of foot:
a. Inversion n eversion occur at subtalar joint
b. Tibialis anterior n tibialis posterior cause inversion
c. Peronei cause eversion
d. Aschli tendon plays imp role when we r standing on toes
e.
38. 45y lady comes with vaginal bleeding doc advise her for hysterectomy due to premalignant condition which is it?
a. Atypical endometrial hyperplasia
b. Complex endometrial.....
c. Simple endometrial...
d. Squamous metaplasia
e.
39. Child with generalized edema and proteinurea 6g per day which part of the kidney involved
a. Interstitium
b. Basement membrane
c. Collecting tubules
d. Proximal convulated tubules
e. Distal tubules
40. Young female developed acute renal failure after post partum hemorrhage. which part of the kidney is most likely damaged
a. Proximal convuluted tubules
b. Loop of henle
c. Collecting tubules
d. Dital convuluted tubules
e.
41. Regarding neutrophil correct
a. Migrate into and out of blood stream
b. More phagocytic in bloodstream
c. Decrease in infective conditions
d. Decrease when corticosteroid given
e.
42. Initial response to tissue injury is:
a. Vasoconstriction
b. Clot formation
c. Platelet adherence
d.
e.
43. Hypoxia causes vasoconstriction in
a. Pulmonary vasculature
b. Heart
c. Brain
d. Kidney
e.
44. High levels of protein associated with
a. Chylomicrons
b. HDL
c. VLDL
d. LDL
e.
45. After 6 hours of myocardial infarction which enzyme level most raised
a. CPK
b. LDH
c. ALT
d. AST
e. ALKALINE PHOSPHATASE
46. Blood supply of motor cerebral cortex
a. Anterior and middle cerebral artery
b. Anterior and posterior cerebral artery
c. Basillar artery
d.
e.
47. Most common cause of liver cirrhosis in an adult male?
a. Alcoholism
b. Hepatitis B
c. Hepatitis C
d. Hepatitis A
e. Hepatitis D
48. What is most characteristic of cerebral motor cortex
a. is present in frontal lobe
b. Doesn't receive any sensory input
c. is essential to carry out voluntary movements
d. essential for stretch reflex
e.
49. 3rd ventricle, what is most inappropriate
a. choroid plexus is present in its floor
b. choroid plexus is supplied by internal carotid and basillary artery
c. is connected to lateral ventricles via interventricular formina
d. is connected to 4th ventricle via cerebral acqueduct
e. present in midbrain
50. Diff b/w first n second heart sounds...
a. Frequency
b. Duration
c. With carotid pulse
d.
e.
51. Distribution of drug enhanced by?
a. Ionized state
b. Lipid solubility
c. Electric equivalence
d.
e.
52. Right bronchus
a. Is shorter
b. Is vertical
c. is infront of pulm artey
d. is infront of pulm vein
e.
53. Fasting blood sugar of patient is 6.8 mol(122mg/dl) after 1 hour of gtt its 10.9 mol and later after 2 hours post prandial it was 10.7 mol(194 mg/dl) what is the diagnosis..
a. Diabetes mellitus
b. Impaired gluc tolerance
c. long lag phase
d. Secondary diabetes mellitus
e.
54. Ischemia in Diabetes mellitus commonly results from
a. Dry gangrene
b. Gas gangrene
c. Endarteritis obliterans
d. Wet gangrene
e.
55. Rods and cones wid excitatory potentials to ganglion and bipolar cells...which neurotransmitter?
a. GABA
b. Glycine
c. Glutamate
d.
e.
56. Which structure doesn’t lie deep to the parotid gland?
a. Internal jugular vein
b. Internal carotid artery
c. Pharynx
d. Parotid duct
e. x, xi nerves in the carotid sheath
57. Bad news, when delivered to patient, should ideally be
a. At bedside
b. All the staff involved in patient's care should be present
c. In front of all family members
d. In doctor's office, in a formal session, in environment of exclusivity
e.
58. Regarding counseling, when done to pts, is good for
a. Their friends
b. Family members
c. Other pts
d. Themselves
e.
59. Which of the following tumors doesn’t cause distant metastases?
a. basal cell Ca
b. dysgerminoma
c. verucous carcinoma
d. Squamous cell carcinoma
e.
60. cx shows mild dysplasia with squamous vacuoles:
a. CIN 1
b. CIN II
c. CIN III
d. Ca in situ
e. HPV
61. Which one of the following organ is present inside the peritoneal cavity?
a. fallopian tubes
b. ovary
c. gonads
d. first part of the duodenum
e. round ligament of uterus
62. What is the most common cause of increased vascular permeability?
a. Inflammation
b. Trauma
c. Immunological
d. Allergy
e.
63. Regarding Vitamin K
a. is a water soluble vitamin
b. produced by intestinal bacteria
c. present in large amount in human and cow's milk
d. When given in neonatal hemorrhage, prevents coagulation
e.
64. Psoas muscle
a. originate from all lumbar vertebra
b. present b/w lumber plexus
c. passes in front of inguinal ligament
d.
e.
65. Half life of carboxyhaemaglobin.
a. 5 min
b. 2hr
c. 6 hr
d.
e.
66. Regarding icf
a. 2/3 of tbw
b. 1/3 of tbw
c.
d.
e.
67. Which of the following non hairy regions does not have sebacous glands?
a. glans and prepuce of penis
b. labia minora
c. margins of lips
d. palms and soles of feet
e. nipple
68. ESR decreases with increase in:
a. cholesterol in blood
b. inc. globulin
c. plasma albumin
d. fibrinogen
e. temperature
69. Hypokalemia causes which of the following...
a. Hyperpolarization
b. Hyperexcitability
c. decrease in height of action potential
d.
e.
70. An alcoholic patient comes with wernikes korasakoff syndrome. It could be due to def of which of the following vitamins
a. B1
b. A
c. D
d. K
e. C
71. In 90 percent of anthrax infections
a. Hemorrhagic pneumonia
b. gatrointestinal hemorrhage
c. skin lesions
d. bacteremia
e.
72. Not related to spinal cord
a. ant gray horn
b. latearl lemniscus
c. posterolateal sulcus
d. gray commisure
e.
73. Patient presented with painless heamaturia along with fever, night sweats for 2 months, ultrasound abdomen plain is normal, diagnosis is
a. Renal Cell Carcinoma
b. Acute Pyelonephritis
c. Renal tuberculosis
d. Acute tubular Necrosis
e.
74. A patient with cervical lymphadenopathy, CXR shows Bilateral Hilar Lymphadenopathy. Biopsy shows caseating granulomaous pattern, diagnosis is
a. Sarcoidosis
b. Tuberculosis
c.
d.
e.
75. A 21 year old having severe Ulcerative Colitis,which of the following is indicated
a. Azathioprine
b. IV Corticosteroides
c. Sulfasalazine
d.
e.
76. In which of the following conditions,atrial repolarization is evident on ECG
a. 1st degree heart block
b. 3rd degree heart block
c. MI
d. Deep inspiraion
e.
77. Which of the following suppress GH release?
a. Puberty
b. Sleep
c. Somatomedin
d. Starvation
e. Stress
78. Which organ has a highest arteriovenous shunts
a. liver
b. lungs
c. heart
d. kidneys
e.
79. If ejection fraction is increased there will be
a. dec end-systolic volume
b. dec end-diastolic volume
c.
d.
e.
80. Amoebic liver abscess spread to lungs by
a. Direct
b. Lymphatics
c. Haematogenous
d. through diaphragm
e.
81. A pregnant lady has mitral stenosis,, to prevent atrial fibrillaton treatment is
a. im heparin
b. iv heparin
c. heparin and oral anticoagulant
d. oral anticoagulant
e.
82. There was some question from biostats that which is most inappropriate?
a. something was abt variance
b. experimental p<0.05
c. exploratory p<0.01
d. analysis of variance that it can be done by one thing
e.
83. Root value of knee jerk
a. L3 L4
b. s1
c. L1,2
d.
e.
84. A boy engulfs peanut and it got stuck in the air way where would it occlude?
a. right main bronchus
b. right middle broncus
c. right lower bronchus
d. left lower bronchus
e.
85. Which of the following is a tumour supressor gene?
a. Ras
b. bcl2
c. ABL
d.
e.
86. Acidophillic cytoplasm with basophilic granules, structure less material in center, outline irregular
a. karyolysis
b. hydrops degeneration
c. apoptosis
d. hydrolysis
e.
87. Cyclosporin acts by
a. stimulating production of NK cells
b. modifying maturation of T cells
c. inhibiting NK cells
d.
e.
88. How many ATPs are produced after complete metabolism of one molecule of Glucose?
a. 30
b. 32
c. 38
d. 40
e. 44
89. Female child born then sent home. 15 hours later she presented with cyanosis + weak pulse & diagnosis?
a. VSD
b. TRANSPOSITION OF GREAT VESSELS with no communication like VSD/ASD
c. hypoplastic Left ventricle
d. TOF
e. PDA
90. most powerful stimulus for rennin
a. dec NA Cocent to tbules
b. hypotention
c. sympathetic stimulation
d.
e.
91. Dietary fibers
a. Collagens
b. Peptidoglycans
c. Pectin
d. Starc
e.
92. Lymph flow from the foot is
a. increased when an individual rises from the supine to the standing position
b. increased by massaging the foot
c. increased when capillary permeability is decreased
d. decreased when the valves of the leg veins are incompetent
e. decreased by exercise
93. Which of the following is not synthesized in both endocrine glands and the brain?
a. Somatostatin
b. Cortisol
c. Dopamine
d. ACTH
e. Oxytocin
94. Regular rhythmic fluctuations in electrical activity are observed in the cerebral cortex and thalamus. In addition, they are seen in the
a. mediobasal portion of the hypothalamus
b. cerebellar cortex
c. midbrain reticular formation
d. amygdale
e. pons
95. In a healthy, alert adult sitting with the eyes closed, the dominant EEG rhythm observed with electrodes over the occipital lobes is
a. delta (0.5-4 Hz)
b. theta (4-7 Hz)
c. alpha (8-13 Hz)
d. beta (18-30 Hz)
e. fast, irregular low-voltage activity
96. A person cannot differentiate between red n green colour while making presentation on computer, what is the most likely defect in this patient ?
a. Absent rods.
b. Absent cones.
c. macula lutea
d.
e.
97. What will be the symptoms if there is leison in left optic radiation?
a. Blind left eye.
b. rt.homonymous hemianopia.
c. bitemporal hemianopia.
d. binasal hemianopia.
e. lt.homonymous hemianopia
98. In right shift of oxygen dissc. curve the most likely value of T50 would b?
a. 20
b. 18
c. 26
d. 35
e.
99. The part of basal nuclei is.........?
a. putamen.
b. amygdolid.
c. Subthalamus
d. Hypothalamus
e.
100. Isoelectric segment of ECG during which the complete ventricular depolirization occurs
a. QRS
b. QT SEG
c. ST seg
d.
e.
101. 2nd part of duodenum is crossed anteriorly by ......
a. mesocolon attachment
b. left renal vein
c. sup mesenteric artery
d. portal vein
e.
102. adult polycystic kidney disease
a. autisomoal dominant
b. aut.ressecive
c. x linked
d.
e.
103. A male 60 yr Generalized lymphadenopathy, on peri, smear lymphocytes looks mature cell .........
a. CLL
b. CML
c. ALL
d.
e.
104. Damage to median nerve......
a. loss of abduction of thumb
b. loss of adduction of thumb
c. loss off sensattion on lateral side of hand
d.
e.
105. CSF composition approprate is .........
a. 20_40mg/protein
b. Sodium 130 meq/ml
c. Glucose 120mg/dl
d.
e.
106. Internal capsule inapprorate is........
a. ant, and post. limb contains cortiospinal n corticocerbellar fiber
b. sensory fibers pass thru ant limb
c. corona radiate transmit impulses to cortex
d.
e.
107. Primordial germ cells deriveted from..
a. wall of yolk sac.
b. Amnion
c. Trophoblast
d. Deciduas
e.
108. during sleep hormone level is more than awake time
a. cortisol
b. ADH
c. epinephrine
d.
e.
109. anarobes infectionall all true execpt.......
a. granuloma formation
b. gangrene
c. food poisoning
d. necrosis
e. lock jaw
110. male 40 yr,15kg overwt with 20mmol blood sugar i treatment in addition to diet and excirse is
a. biguanides
b. glybenclamide
c. acarbose
d.
e.
111. Myasthenia garvis diz is......
a. type 2 H.S reaction
b. type 1
c. type 3
d. type 4
e.
112. poststreptococcal G.N is,,,,
a. type 2 H.S reaction
b. type 1
c. type 3
d. type 4
e.
113. Water flow from plasma to interstial fluid
a. filtration.
b. with sodium
c. active process
d. facilitated transport
e.
114. lymph filtration in spleen occurs in
a. penicillus arteries
b. trabicular
c. centre
d. peripheral
e.
115. Venous blood from the leg is increased during exercise,,
a. muscle contration of leg
b. valve in veins may be
c. intra thoracic pressure
d.
e.
116. Optic chiasma lesion causes..
a. bitemporal hemianopia
b. rt homonymeous hemianopia
c. lt..homonymeous hemianopia
d.
e.
117. father A ,,mother AB ,,fetus will never have blood group ……….
a. O
b. B
c. AB
d. A
e.
118. Mother –ve , father +ve 1st child with hepatospleenomegaly now 2nd child (erythroblastosis fetalesis),, baby has blood group….
a. O+ve
b. O-ve
c. B-ve
d.
e.
119. Pituitary gland not related with…..
a. facial nerve
b. sphenoid sinus
c. cavvernous sinuus
d. optic chiasma
e.
120. lady with PPH can not lactate her baby inspite of willing for lactation due to
a. sheehans synd..
b. anemia
c. fibroid
d. endometrial hyperplasia
e.
121. Female patient having ch, renal failure ,,best donor for transplatation ..
a. twin
b. husband
c. step sister
d. step brother
e.
122. In saliva bactriocidal agent is ……..
a. lysozymes
b. lysosome
c. acid
d. amylin
e. IgA
123. Rationale treatment of essenial HTN
a. alpha blkers
b. aldosterone
c. Angiotensin receptor blocker
d.
e.
124. Antibiotic given with serum conc, mointering ..
a. vancomycin
b. cyclosporine
c. omeprazole
d.
e.
125. Gardeners spraying inscticieds become sunconseous, salivation. drug to be given to antagonize symptoms ….
a. Pralidoxime
b. Atropine
c. Epinephrine
d.
e.
126. Adrenal glands blood supply most inappropriately..
a. all branches of arteries from aorta.
b. 1 branch from renal art
c. 1 br from phrenic
d.
e.
127. Nephrotic synd, with Generalized .edema due to….
a. dec, colloidal osmotic pressure
b. dec hydrostatic pressure
c. dec salt retention
d.
e.
128. ADH dec. by ……
a. Alcohol
b. Aldosterone
c. inc salt
d. decrease body water
e. starvation
129. PPI’s drug is …
a. omeprazole.
b. Cimetidine
c. Metoclopramide
d.
e.
130. H2 blockers …
a. dec HCL secretion
b. delay gastric emptying
c. inc hcl
d.
e.
131. Which is not immunosuprresnt…?
a. anticholerngic agent
b. corticosteroid
c. methotrexate
d.
e.
132. Which is not malignant lesion
a. Osteomlytis
b. Ulcerative colitis
c. Erythroplakia
d. sarcoidosis
e.
133. Swallowing stage…
a. Palantopharngeus muscles moves laterally
b. Larynx moves down
c. Palate move downwards
d.
e.
134. Basophilia of cell due to…
a. RER
b. golgi bodies
c. nnucleus
d.
e.
135. CIN of cervix most easy cheaper and valuable tst ..
a. pap smear
b. ultrasound
c. D n C
d.
e.
136. Correct about ureter………
a. enter rt angle in blabber
b. lies above utrine artery
c. is not close to cervix
d. present in broad ligament
e. posteriorly external ilaic vessels
137. regarding posteror mediastinum,,,,
a. aorta gives 9 post intercostal br
b. all intercostals veins drain into azygous vein
c. Thoracic duct turn to left side
d.
e.
138. 3rd part of subclavian artery anyersum swelling present in…
a. ant triangle
b. post triangle
c. axilla
d.
e.
139. Ventilation is very high at ….
a. apex of lung
b. base of lung
c. middlle zone
d.
e.
140. Pacemaker for cerebral cortex which show changes on EEG ….
a. Thalamus
b. reticular formation
c. hypothalamus
d.
e.
141. Nigrostratail fibers secrete neurotransmitter …
a. dopamine
b. Ach
c. Seotonin
d.
e.
142. Hormone causing Gluconeogenesis …
a. glucogan.
b. GH
c. ADH
d. Insulin
e.
143. Patient with fever ,joint pain ,chest infection, anemia,, HB type present will be
a. HB ss
b. HBsc
c. HB A2
d.
e.
144. Ac ventricular failure, resp distress, drug of choice is…
a. i/v frisemide
b. dopamine
c. streptokinase
d. oxygen
e.
145. Thyroid gland ..
a. Histological active follicles contain more colloid
b. start at uppper border of thyroid cartilage
c. isthamus at c123
d.
e.
146. Sympathetic block to urinary baldder, which will result??
a. pain n filling sensation lost
b. unable to empty bladder
c. inc tone of int.bladder sphincter
d. dec tone of ext.bladder sphincter
e. inc male fertility
147. Vagal stimulation result in..
a. inc gasticc emptying
b. dec gasticc emptying
c. block acid secretion
d.
e.
148. Tumor with least likely metastasis
a. BCC
b. SCC
c. lymphoma
d.
e.
149. Which of the following drug irreversibly blocks platelet action…
a. asprin
b. naproxen
c. diclofenac
d.
e.
150. patient wth BT prolong ,normal CT ,normal Aptt with clott retriction problem
a. afibrinogenmia
b. thrompocytopenia
c. hemophilia
d.
e.
151. FEMALE hyperthoriodism with palpitaion and tachycardia, pulse rate 110, all these findings are due to…
a. beta adrenergic response
b. Alpha adrenergic
c. vagus stimulation
d.
e.
152. Pul.O2 toxicity result from
a. prolong o2 therapy
b. inc PCO2
c. at high altitude
d. in under water
e.
153. Clinically, GFR is measured by
a. creatine
b. inulin
c. PAH
d.
e.
154. About ansa cervicalis……..all are correct except
a. supply to carotid body
b. c1,2,3
c. joins hypoglossal
d. supply thyrohyoid muscle
e.
155. Inappropriate for type 2 Hyper.Sensitivity..
a. mast basophiles ,platelates degranulation play major role
b. antibody antigen complex
c. circulating complex
156. Which one of the following is correct
a.csf production is 500ml/day
b. hyperkalemia occurs in sever diabetes mellitus
c. 98 % potassium is present intra cellularly
157. Heparin prevent thrombus
a. propagation
b. embolization
c. formation
d. organization
158. Anti thrombin 3 is activated by
a. heparin
b. warferine
c.PAF
d.VWF
159. Which of the following organism produce hemorrhagic fever when person is infected for the 2nd time
a.CMV
b.HSV
c. dengue
d. rubella
160. Which of the following is inappropriate
a. hyperplasia is inc in number of cell
b. hypertophy is inc in size
c. hyperplasia n hypertrophy can not occur in the same tissue
161. Regarding parasympathetic stimulation
a. increase PR interval
b. decrease PR interval
c. decrease QRS interval
162. In case of hyperthyroidism, which is inappropriate
a. increase bone demineralization
b. calciuria
c. hyper phosphatemia
d. hypercalcemia
e.hyperphosphaturia
163. At alveolar level, microbicidal function is done by
a. alveolar macrophages
b. IgA
c. mucus
164. A patient has bone sarcoma, radiations were given,, after some days patient developed skin ulcer at site of radiation, which is not healing. This is most likely due to
a. endartritus obliterans
b. infection
c. malignancy
d. venous thrombosis
165. O2 n H2O2 is produced in neutrophil from
a. peroxisome
b. mitochondria
c. lysosome
d.RER
e. nucleus
166. Respiratory center in brain is sensitive to changes in
a.PCO2
b.PO2
c. pH
d. H ion concentration
167. Regarding Opiods
a. can be safely given with mono amine oxidase inhibitor
b. can be given in increased intra cranial pressure
c. older persons are less sensitive to it, so increase dose should be given
168. In which of the following vein venous PaO2 n PaCO2 is appropriate with arterial blood
a. femoral vein
b. anticubetal vein
c. intenal juglar vein
d. subclavian vein
e. veins on dorsum of a warm hand
169. External carotid artey is differentiated from internal carotid artery
a. more pulsatile
b. branches in neck
c. deep
170. A person after some kind of thermal stress, was found to be unconscious, on examination he has cold clamy extremities, core body temperature 99 F, n has hypotension,, which of the following phenonmenon occurred
a. heat exhaustion
b. heat stroke
c. hypoyhermia
171. A patient has pituitary tumor, in addition to blindness from compression of optic chiasma, it has also eroded lower part of hypo thalamus. Which of the following will result from hypothalamus lesion
a. hyperphagia
b. hyperthermia
c. hypothermia
172. Most common congenital heart disease
a. ASD
b. VSD
c. TOF
d.PDA
173. Which of the following autoimmune disease involves only single organ
a. SLE
b. RA
c. cystic fibrosis
174. EBV causes which malignancy
a. nasopharyngeal carcinoma
b. kaposi sarcoma
c. burkitt’s lymphoma
175. About chalamydia
a. cause choriorretinitis
b. cause trachoma
c. is aerobic organism
d. is club shaped
176. When loop diuretic given, which one of the following is correct
a. dec interstitium osmolality,so dilute uurine is produced
b. dec osmolality of tubular fluid
c. dec calcium in urine
d. dec urea secreted in urine
177. Central artey of retina is related to
a. superior orbital fissure
b. inferior orbital fissure
c. optic canal
d. cavernous sinus
e. facial vein
178. Turbulence in vessel is increased by increase in
a. diameter
b. velocity
c. radius
d. viscosity
179. About broncho pulmonary segment
a. supplied by tertiary bronchiole
b. is independent of each other
c. artey is anterior to bronchus
d. vein is posterior to bronchus
180. Osmlarity increase with increase in
a. number of solute particles
b. size of solute particles
c. molecular weight of solute particles
181. Blood supply of stomach
a. right gastric artery supply lesser curvature
b. right gastroepiploic artey is branch of gastrodudenal artery
c. short gastric artery is branch of hepatic artery
182. What is true regarding fibroadenoma of the breast ?
a. posterior acoustic enhancement in less than 50%
b. is likely to be tender to palpation
c. macro calcifications are usually seen
d. regresses after menopause
e. the presence of a halo is an ominous sign
183. Medullary branch of vertebral artery is damaged on right side, which of the following will result
a. loss of hypoglossal nerve function on same side
b. loss of hypoglossal function on opposite side
c. loss of all sensation on opposite side
d. loss of voluntary movement on opposite side
184. Insulin secretion is decreased by
a. glucagon secretion
b. food intake
c. somatostatin release
d. pituitary gland
185. Connective tissue in all body except head n neck, is derived from
a. ectoderm
b. endoderm
c. mesoderm
d. ecto + meso
e. meso +endo
a. Migration of tumor cells
b. Breakdown of e-cadherin
c. sepeation of tumor cells from one another
d. Damaging extracellular matrix
e.
2. What is most common cause of congenital hypothyroidism:
a. Maternal iodide deficiency
b. Inborn error of metabolism
c. Defective embryogenesis
d. Antibodies against thyroid hormone crossing placenta
e.
3. Diabetic pat taking oral hypoglycemic drugs complain of abdominal fullness, which drug can b given to decrease gastropresis
a. Omeprazol
b. Cimetidine
c. Antacids
d. Metclopramide
e.
4. On motor bike accident fracture of neck of humerus n can,t abduct his arm.due to
a. Axillary nerve
b. Long thoracic nerve
c. Musculocutaneous nerve
d.
e.
5. Regarding trachea
a. Gap in the C shape cartilages are lying anteriorly
b. 15 cm in length
c. Recurrent laryngeal nerve pases anteriorly
d. Isthmus of thyroid lying in front of 4rt or 5th tracheal ring
e. Starts at the lower border of cricoid cartilage
6. Release of acid from stomach is mediated through
a. H1 receptor
b. H2 receptor
c. food in stomach
d.
e.
7. Diaphragm is supplied by
a. C3
b. C3,4,5
c. C4,5
d. C4,5,6
e.
8. A female at 36weeks gestation cmwith bili;20mg/dl raised SGPT & SGOT.she has returned from remote village. What can b the cause of infection?
a. HAV
b. HBV
c. HCV
d. HEV
e.
9. What is the structure arches around the root of left lung
a. Azygus vein
b. Arch of aorta
c. Left phrenic nerve
d. Left vagus nerve
e. Left recurrent laryngeal nerve
10. Regarding ESR decreased by increase in which of the following
a. Increase plasma globulin
b. Increase fibrinogen
c. Increase plasma Albumin
d. Increase globulin and albumin ratio
e. Temperature
11. Best example of pharmaco kinetics drug drug interaction:
a. Iincrease action of procain by epinephrine
b. Increase action of........... by Calcium
c. Toxicity of lithium with thiazide diuretics
d. Reverse the action of aspirin by NaHCO3
e. Reverse the action of Morphine by Naloxone
12. Following veins drain into coronay sinus, which vein continues as coronary sinus
a. Middle cardiac vein
b. Great cardiac vein
c. Anterior cardiac vein
d. Oblique vein
e.
13. Notochord arises from
a. Ectoderm
b. Mesoderm
c. Endoderm
d.
e.
14. Thyroid is derived from
a. Ectoderm
b. Mesoderm
c. Endoderm
d.
e.
15. Which one of the following is a chemical carcinogen
a. Alpha 1 antitrypsin
b. Benzidine
c. Ethyl alcohol
d. Propyl alcohol
e.
16. Contractile unit in skeletal muscle is between
a. h discs
b. z lines
c. t tubules
d.
e.
17. A/P radiograph of chest which structure forms right border of heart
a. SVC
b. IVC
c. Right ventricle
d. Arch of aorta
e. Left Atrium
18. 60 percent of work of breathing
a. is to overcome elastic recoil of lungs
b. Counteract chest wall compliance
c. Resistance offered by small size bronchi
d. Resistance by large bronchi
e.
19. Regarding nerve supply to skeletal muscle contains
a. 60%motor 40%sensory fibers
b. 40%motor 60%sensory
c. 60%motor 40%sensory and few postganglionic sympathetic fibers
d.
e.
20. Thirst stimulated by
a. ECF volume depletion
b. ICF volume depletion
c. Salt depletion
d.
e.
21. Regeneration least effected by
a. Diabetes
b. Infection
c. Uv light
d. corticosteroid
e.
22. In downs syndrome at 40 years of age
a. Alzhiemers disease
b. Stroke due to essential hypertension
c. Upper motor neuron lesion
d. Lower motor neuron lesion
e.
23. Primary cartilaginous joint
a. Costochondral
b. Teeth and jaw
c. Inferior tibiofibular joint
d. Symphysis Pubis
e.
24. Epinephrine reuptake by
a. Diffusion and reuptake
b. Diffusion, reuptake and enzyme catalysis
c. Diffusion
d. Reuptake
e. Enzyme catalysis
25. 2 yr old child presented with anemia and has hyper segmented neutrophil, MCV raised, how will you confirm your diagnosis
a. Intrinsic factor antibodies
b. Vit b12 level
c. Transcobalamin
d.
e.
26. Thrombus formation triad
a. Endothelial damage, slow blood flow, altered blood constituents
b. Endothelial damage; high blood flow, fibrin
c. Endo damage eddy blood flow
d. Plasma high blood flow
e.
27. After 6 hours of myocardial infarction which enzyme level most raised
a. CPK
b. LDH
c. ALT
d. AST
e. ALKALINE PHOSPHATASE
28. In adult female breast atrophy is commonly due to decrease
a. Estrogen
b. Estrogen and progesterone
c. Progesterone
d. Prolactin
e.
29. Patient taking MAO inhibitors, taking which of the following could cause hypertensive crisis?
a. Coffee
b. Chocolate
c. Cola
d. Pine apple
e. String beans
30. Left kidney is not related anteriorly to which of the following structures?
a. Diaphragm
b. Stomach
c. Pancrease
d. Spleen and splenic vessels
e. Splenic flexure of transverse colon
31. A 30 year man participated in marathon race the most common hormone changes you will find
a. Low Insulin, High Glucagon
b. Low Insulin, Low Glucagon
c. High Insulin, High Glucagon
d. High Insulin, Low Glucagon
e.
32. 2x2 table in biostats?
a. T-Test
b. Chi Square Test
c.
d.
e.
33. Which of the following lymphoid structure does NOT contain lymph nodules:
a. Spleen
b. Lymph node
c. Thymus
d. Payer's patches
e. Tonsils
34. A person has pH 7.48, CO2 66 and HCO3 27 . What is the diagnosis
a. Acute respiratory acidosis
b. Acute metabolic acidosis
c. Partially compensated respiratory acidosis
d. Partially compensated metabolic acidosis
e. Partially compensated metabolic alkalosis
35. A patient suffers from appendicitis. Peripheral blood shows leukocytosis. Pain will be mediated by
a. IL 1 and TNF alpha
b. Bradykinin and prostaglandin E
c. Serotonin
d. IL 6
e. enkephalin
36. In myocardial infarction, which earliest change occurs in formation of aschoff bodies
a. Fibrinoid necrosis
b. Inflamaton
c. Giant cell
d. Eosinophilia
e.
37. Regarding movements of foot:
a. Inversion n eversion occur at subtalar joint
b. Tibialis anterior n tibialis posterior cause inversion
c. Peronei cause eversion
d. Aschli tendon plays imp role when we r standing on toes
e.
38. 45y lady comes with vaginal bleeding doc advise her for hysterectomy due to premalignant condition which is it?
a. Atypical endometrial hyperplasia
b. Complex endometrial.....
c. Simple endometrial...
d. Squamous metaplasia
e.
39. Child with generalized edema and proteinurea 6g per day which part of the kidney involved
a. Interstitium
b. Basement membrane
c. Collecting tubules
d. Proximal convulated tubules
e. Distal tubules
40. Young female developed acute renal failure after post partum hemorrhage. which part of the kidney is most likely damaged
a. Proximal convuluted tubules
b. Loop of henle
c. Collecting tubules
d. Dital convuluted tubules
e.
41. Regarding neutrophil correct
a. Migrate into and out of blood stream
b. More phagocytic in bloodstream
c. Decrease in infective conditions
d. Decrease when corticosteroid given
e.
42. Initial response to tissue injury is:
a. Vasoconstriction
b. Clot formation
c. Platelet adherence
d.
e.
43. Hypoxia causes vasoconstriction in
a. Pulmonary vasculature
b. Heart
c. Brain
d. Kidney
e.
44. High levels of protein associated with
a. Chylomicrons
b. HDL
c. VLDL
d. LDL
e.
45. After 6 hours of myocardial infarction which enzyme level most raised
a. CPK
b. LDH
c. ALT
d. AST
e. ALKALINE PHOSPHATASE
46. Blood supply of motor cerebral cortex
a. Anterior and middle cerebral artery
b. Anterior and posterior cerebral artery
c. Basillar artery
d.
e.
47. Most common cause of liver cirrhosis in an adult male?
a. Alcoholism
b. Hepatitis B
c. Hepatitis C
d. Hepatitis A
e. Hepatitis D
48. What is most characteristic of cerebral motor cortex
a. is present in frontal lobe
b. Doesn't receive any sensory input
c. is essential to carry out voluntary movements
d. essential for stretch reflex
e.
49. 3rd ventricle, what is most inappropriate
a. choroid plexus is present in its floor
b. choroid plexus is supplied by internal carotid and basillary artery
c. is connected to lateral ventricles via interventricular formina
d. is connected to 4th ventricle via cerebral acqueduct
e. present in midbrain
50. Diff b/w first n second heart sounds...
a. Frequency
b. Duration
c. With carotid pulse
d.
e.
51. Distribution of drug enhanced by?
a. Ionized state
b. Lipid solubility
c. Electric equivalence
d.
e.
52. Right bronchus
a. Is shorter
b. Is vertical
c. is infront of pulm artey
d. is infront of pulm vein
e.
53. Fasting blood sugar of patient is 6.8 mol(122mg/dl) after 1 hour of gtt its 10.9 mol and later after 2 hours post prandial it was 10.7 mol(194 mg/dl) what is the diagnosis..
a. Diabetes mellitus
b. Impaired gluc tolerance
c. long lag phase
d. Secondary diabetes mellitus
e.
54. Ischemia in Diabetes mellitus commonly results from
a. Dry gangrene
b. Gas gangrene
c. Endarteritis obliterans
d. Wet gangrene
e.
55. Rods and cones wid excitatory potentials to ganglion and bipolar cells...which neurotransmitter?
a. GABA
b. Glycine
c. Glutamate
d.
e.
56. Which structure doesn’t lie deep to the parotid gland?
a. Internal jugular vein
b. Internal carotid artery
c. Pharynx
d. Parotid duct
e. x, xi nerves in the carotid sheath
57. Bad news, when delivered to patient, should ideally be
a. At bedside
b. All the staff involved in patient's care should be present
c. In front of all family members
d. In doctor's office, in a formal session, in environment of exclusivity
e.
58. Regarding counseling, when done to pts, is good for
a. Their friends
b. Family members
c. Other pts
d. Themselves
e.
59. Which of the following tumors doesn’t cause distant metastases?
a. basal cell Ca
b. dysgerminoma
c. verucous carcinoma
d. Squamous cell carcinoma
e.
60. cx shows mild dysplasia with squamous vacuoles:
a. CIN 1
b. CIN II
c. CIN III
d. Ca in situ
e. HPV
61. Which one of the following organ is present inside the peritoneal cavity?
a. fallopian tubes
b. ovary
c. gonads
d. first part of the duodenum
e. round ligament of uterus
62. What is the most common cause of increased vascular permeability?
a. Inflammation
b. Trauma
c. Immunological
d. Allergy
e.
63. Regarding Vitamin K
a. is a water soluble vitamin
b. produced by intestinal bacteria
c. present in large amount in human and cow's milk
d. When given in neonatal hemorrhage, prevents coagulation
e.
64. Psoas muscle
a. originate from all lumbar vertebra
b. present b/w lumber plexus
c. passes in front of inguinal ligament
d.
e.
65. Half life of carboxyhaemaglobin.
a. 5 min
b. 2hr
c. 6 hr
d.
e.
66. Regarding icf
a. 2/3 of tbw
b. 1/3 of tbw
c.
d.
e.
67. Which of the following non hairy regions does not have sebacous glands?
a. glans and prepuce of penis
b. labia minora
c. margins of lips
d. palms and soles of feet
e. nipple
68. ESR decreases with increase in:
a. cholesterol in blood
b. inc. globulin
c. plasma albumin
d. fibrinogen
e. temperature
69. Hypokalemia causes which of the following...
a. Hyperpolarization
b. Hyperexcitability
c. decrease in height of action potential
d.
e.
70. An alcoholic patient comes with wernikes korasakoff syndrome. It could be due to def of which of the following vitamins
a. B1
b. A
c. D
d. K
e. C
71. In 90 percent of anthrax infections
a. Hemorrhagic pneumonia
b. gatrointestinal hemorrhage
c. skin lesions
d. bacteremia
e.
72. Not related to spinal cord
a. ant gray horn
b. latearl lemniscus
c. posterolateal sulcus
d. gray commisure
e.
73. Patient presented with painless heamaturia along with fever, night sweats for 2 months, ultrasound abdomen plain is normal, diagnosis is
a. Renal Cell Carcinoma
b. Acute Pyelonephritis
c. Renal tuberculosis
d. Acute tubular Necrosis
e.
74. A patient with cervical lymphadenopathy, CXR shows Bilateral Hilar Lymphadenopathy. Biopsy shows caseating granulomaous pattern, diagnosis is
a. Sarcoidosis
b. Tuberculosis
c.
d.
e.
75. A 21 year old having severe Ulcerative Colitis,which of the following is indicated
a. Azathioprine
b. IV Corticosteroides
c. Sulfasalazine
d.
e.
76. In which of the following conditions,atrial repolarization is evident on ECG
a. 1st degree heart block
b. 3rd degree heart block
c. MI
d. Deep inspiraion
e.
77. Which of the following suppress GH release?
a. Puberty
b. Sleep
c. Somatomedin
d. Starvation
e. Stress
78. Which organ has a highest arteriovenous shunts
a. liver
b. lungs
c. heart
d. kidneys
e.
79. If ejection fraction is increased there will be
a. dec end-systolic volume
b. dec end-diastolic volume
c.
d.
e.
80. Amoebic liver abscess spread to lungs by
a. Direct
b. Lymphatics
c. Haematogenous
d. through diaphragm
e.
81. A pregnant lady has mitral stenosis,, to prevent atrial fibrillaton treatment is
a. im heparin
b. iv heparin
c. heparin and oral anticoagulant
d. oral anticoagulant
e.
82. There was some question from biostats that which is most inappropriate?
a. something was abt variance
b. experimental p<0.05
c. exploratory p<0.01
d. analysis of variance that it can be done by one thing
e.
83. Root value of knee jerk
a. L3 L4
b. s1
c. L1,2
d.
e.
84. A boy engulfs peanut and it got stuck in the air way where would it occlude?
a. right main bronchus
b. right middle broncus
c. right lower bronchus
d. left lower bronchus
e.
85. Which of the following is a tumour supressor gene?
a. Ras
b. bcl2
c. ABL
d.
e.
86. Acidophillic cytoplasm with basophilic granules, structure less material in center, outline irregular
a. karyolysis
b. hydrops degeneration
c. apoptosis
d. hydrolysis
e.
87. Cyclosporin acts by
a. stimulating production of NK cells
b. modifying maturation of T cells
c. inhibiting NK cells
d.
e.
88. How many ATPs are produced after complete metabolism of one molecule of Glucose?
a. 30
b. 32
c. 38
d. 40
e. 44
89. Female child born then sent home. 15 hours later she presented with cyanosis + weak pulse & diagnosis?
a. VSD
b. TRANSPOSITION OF GREAT VESSELS with no communication like VSD/ASD
c. hypoplastic Left ventricle
d. TOF
e. PDA
90. most powerful stimulus for rennin
a. dec NA Cocent to tbules
b. hypotention
c. sympathetic stimulation
d.
e.
91. Dietary fibers
a. Collagens
b. Peptidoglycans
c. Pectin
d. Starc
e.
92. Lymph flow from the foot is
a. increased when an individual rises from the supine to the standing position
b. increased by massaging the foot
c. increased when capillary permeability is decreased
d. decreased when the valves of the leg veins are incompetent
e. decreased by exercise
93. Which of the following is not synthesized in both endocrine glands and the brain?
a. Somatostatin
b. Cortisol
c. Dopamine
d. ACTH
e. Oxytocin
94. Regular rhythmic fluctuations in electrical activity are observed in the cerebral cortex and thalamus. In addition, they are seen in the
a. mediobasal portion of the hypothalamus
b. cerebellar cortex
c. midbrain reticular formation
d. amygdale
e. pons
95. In a healthy, alert adult sitting with the eyes closed, the dominant EEG rhythm observed with electrodes over the occipital lobes is
a. delta (0.5-4 Hz)
b. theta (4-7 Hz)
c. alpha (8-13 Hz)
d. beta (18-30 Hz)
e. fast, irregular low-voltage activity
96. A person cannot differentiate between red n green colour while making presentation on computer, what is the most likely defect in this patient ?
a. Absent rods.
b. Absent cones.
c. macula lutea
d.
e.
97. What will be the symptoms if there is leison in left optic radiation?
a. Blind left eye.
b. rt.homonymous hemianopia.
c. bitemporal hemianopia.
d. binasal hemianopia.
e. lt.homonymous hemianopia
98. In right shift of oxygen dissc. curve the most likely value of T50 would b?
a. 20
b. 18
c. 26
d. 35
e.
99. The part of basal nuclei is.........?
a. putamen.
b. amygdolid.
c. Subthalamus
d. Hypothalamus
e.
100. Isoelectric segment of ECG during which the complete ventricular depolirization occurs
a. QRS
b. QT SEG
c. ST seg
d.
e.
101. 2nd part of duodenum is crossed anteriorly by ......
a. mesocolon attachment
b. left renal vein
c. sup mesenteric artery
d. portal vein
e.
102. adult polycystic kidney disease
a. autisomoal dominant
b. aut.ressecive
c. x linked
d.
e.
103. A male 60 yr Generalized lymphadenopathy, on peri, smear lymphocytes looks mature cell .........
a. CLL
b. CML
c. ALL
d.
e.
104. Damage to median nerve......
a. loss of abduction of thumb
b. loss of adduction of thumb
c. loss off sensattion on lateral side of hand
d.
e.
105. CSF composition approprate is .........
a. 20_40mg/protein
b. Sodium 130 meq/ml
c. Glucose 120mg/dl
d.
e.
106. Internal capsule inapprorate is........
a. ant, and post. limb contains cortiospinal n corticocerbellar fiber
b. sensory fibers pass thru ant limb
c. corona radiate transmit impulses to cortex
d.
e.
107. Primordial germ cells deriveted from..
a. wall of yolk sac.
b. Amnion
c. Trophoblast
d. Deciduas
e.
108. during sleep hormone level is more than awake time
a. cortisol
b. ADH
c. epinephrine
d.
e.
109. anarobes infectionall all true execpt.......
a. granuloma formation
b. gangrene
c. food poisoning
d. necrosis
e. lock jaw
110. male 40 yr,15kg overwt with 20mmol blood sugar i treatment in addition to diet and excirse is
a. biguanides
b. glybenclamide
c. acarbose
d.
e.
111. Myasthenia garvis diz is......
a. type 2 H.S reaction
b. type 1
c. type 3
d. type 4
e.
112. poststreptococcal G.N is,,,,
a. type 2 H.S reaction
b. type 1
c. type 3
d. type 4
e.
113. Water flow from plasma to interstial fluid
a. filtration.
b. with sodium
c. active process
d. facilitated transport
e.
114. lymph filtration in spleen occurs in
a. penicillus arteries
b. trabicular
c. centre
d. peripheral
e.
115. Venous blood from the leg is increased during exercise,,
a. muscle contration of leg
b. valve in veins may be
c. intra thoracic pressure
d.
e.
116. Optic chiasma lesion causes..
a. bitemporal hemianopia
b. rt homonymeous hemianopia
c. lt..homonymeous hemianopia
d.
e.
117. father A ,,mother AB ,,fetus will never have blood group ……….
a. O
b. B
c. AB
d. A
e.
118. Mother –ve , father +ve 1st child with hepatospleenomegaly now 2nd child (erythroblastosis fetalesis),, baby has blood group….
a. O+ve
b. O-ve
c. B-ve
d.
e.
119. Pituitary gland not related with…..
a. facial nerve
b. sphenoid sinus
c. cavvernous sinuus
d. optic chiasma
e.
120. lady with PPH can not lactate her baby inspite of willing for lactation due to
a. sheehans synd..
b. anemia
c. fibroid
d. endometrial hyperplasia
e.
121. Female patient having ch, renal failure ,,best donor for transplatation ..
a. twin
b. husband
c. step sister
d. step brother
e.
122. In saliva bactriocidal agent is ……..
a. lysozymes
b. lysosome
c. acid
d. amylin
e. IgA
123. Rationale treatment of essenial HTN
a. alpha blkers
b. aldosterone
c. Angiotensin receptor blocker
d.
e.
124. Antibiotic given with serum conc, mointering ..
a. vancomycin
b. cyclosporine
c. omeprazole
d.
e.
125. Gardeners spraying inscticieds become sunconseous, salivation. drug to be given to antagonize symptoms ….
a. Pralidoxime
b. Atropine
c. Epinephrine
d.
e.
126. Adrenal glands blood supply most inappropriately..
a. all branches of arteries from aorta.
b. 1 branch from renal art
c. 1 br from phrenic
d.
e.
127. Nephrotic synd, with Generalized .edema due to….
a. dec, colloidal osmotic pressure
b. dec hydrostatic pressure
c. dec salt retention
d.
e.
128. ADH dec. by ……
a. Alcohol
b. Aldosterone
c. inc salt
d. decrease body water
e. starvation
129. PPI’s drug is …
a. omeprazole.
b. Cimetidine
c. Metoclopramide
d.
e.
130. H2 blockers …
a. dec HCL secretion
b. delay gastric emptying
c. inc hcl
d.
e.
131. Which is not immunosuprresnt…?
a. anticholerngic agent
b. corticosteroid
c. methotrexate
d.
e.
132. Which is not malignant lesion
a. Osteomlytis
b. Ulcerative colitis
c. Erythroplakia
d. sarcoidosis
e.
133. Swallowing stage…
a. Palantopharngeus muscles moves laterally
b. Larynx moves down
c. Palate move downwards
d.
e.
134. Basophilia of cell due to…
a. RER
b. golgi bodies
c. nnucleus
d.
e.
135. CIN of cervix most easy cheaper and valuable tst ..
a. pap smear
b. ultrasound
c. D n C
d.
e.
136. Correct about ureter………
a. enter rt angle in blabber
b. lies above utrine artery
c. is not close to cervix
d. present in broad ligament
e. posteriorly external ilaic vessels
137. regarding posteror mediastinum,,,,
a. aorta gives 9 post intercostal br
b. all intercostals veins drain into azygous vein
c. Thoracic duct turn to left side
d.
e.
138. 3rd part of subclavian artery anyersum swelling present in…
a. ant triangle
b. post triangle
c. axilla
d.
e.
139. Ventilation is very high at ….
a. apex of lung
b. base of lung
c. middlle zone
d.
e.
140. Pacemaker for cerebral cortex which show changes on EEG ….
a. Thalamus
b. reticular formation
c. hypothalamus
d.
e.
141. Nigrostratail fibers secrete neurotransmitter …
a. dopamine
b. Ach
c. Seotonin
d.
e.
142. Hormone causing Gluconeogenesis …
a. glucogan.
b. GH
c. ADH
d. Insulin
e.
143. Patient with fever ,joint pain ,chest infection, anemia,, HB type present will be
a. HB ss
b. HBsc
c. HB A2
d.
e.
144. Ac ventricular failure, resp distress, drug of choice is…
a. i/v frisemide
b. dopamine
c. streptokinase
d. oxygen
e.
145. Thyroid gland ..
a. Histological active follicles contain more colloid
b. start at uppper border of thyroid cartilage
c. isthamus at c123
d.
e.
146. Sympathetic block to urinary baldder, which will result??
a. pain n filling sensation lost
b. unable to empty bladder
c. inc tone of int.bladder sphincter
d. dec tone of ext.bladder sphincter
e. inc male fertility
147. Vagal stimulation result in..
a. inc gasticc emptying
b. dec gasticc emptying
c. block acid secretion
d.
e.
148. Tumor with least likely metastasis
a. BCC
b. SCC
c. lymphoma
d.
e.
149. Which of the following drug irreversibly blocks platelet action…
a. asprin
b. naproxen
c. diclofenac
d.
e.
150. patient wth BT prolong ,normal CT ,normal Aptt with clott retriction problem
a. afibrinogenmia
b. thrompocytopenia
c. hemophilia
d.
e.
151. FEMALE hyperthoriodism with palpitaion and tachycardia, pulse rate 110, all these findings are due to…
a. beta adrenergic response
b. Alpha adrenergic
c. vagus stimulation
d.
e.
152. Pul.O2 toxicity result from
a. prolong o2 therapy
b. inc PCO2
c. at high altitude
d. in under water
e.
153. Clinically, GFR is measured by
a. creatine
b. inulin
c. PAH
d.
e.
154. About ansa cervicalis……..all are correct except
a. supply to carotid body
b. c1,2,3
c. joins hypoglossal
d. supply thyrohyoid muscle
e.
155. Inappropriate for type 2 Hyper.Sensitivity..
a. mast basophiles ,platelates degranulation play major role
b. antibody antigen complex
c. circulating complex
156. Which one of the following is correct
a.csf production is 500ml/day
b. hyperkalemia occurs in sever diabetes mellitus
c. 98 % potassium is present intra cellularly
157. Heparin prevent thrombus
a. propagation
b. embolization
c. formation
d. organization
158. Anti thrombin 3 is activated by
a. heparin
b. warferine
c.PAF
d.VWF
159. Which of the following organism produce hemorrhagic fever when person is infected for the 2nd time
a.CMV
b.HSV
c. dengue
d. rubella
160. Which of the following is inappropriate
a. hyperplasia is inc in number of cell
b. hypertophy is inc in size
c. hyperplasia n hypertrophy can not occur in the same tissue
161. Regarding parasympathetic stimulation
a. increase PR interval
b. decrease PR interval
c. decrease QRS interval
162. In case of hyperthyroidism, which is inappropriate
a. increase bone demineralization
b. calciuria
c. hyper phosphatemia
d. hypercalcemia
e.hyperphosphaturia
163. At alveolar level, microbicidal function is done by
a. alveolar macrophages
b. IgA
c. mucus
164. A patient has bone sarcoma, radiations were given,, after some days patient developed skin ulcer at site of radiation, which is not healing. This is most likely due to
a. endartritus obliterans
b. infection
c. malignancy
d. venous thrombosis
165. O2 n H2O2 is produced in neutrophil from
a. peroxisome
b. mitochondria
c. lysosome
d.RER
e. nucleus
166. Respiratory center in brain is sensitive to changes in
a.PCO2
b.PO2
c. pH
d. H ion concentration
167. Regarding Opiods
a. can be safely given with mono amine oxidase inhibitor
b. can be given in increased intra cranial pressure
c. older persons are less sensitive to it, so increase dose should be given
168. In which of the following vein venous PaO2 n PaCO2 is appropriate with arterial blood
a. femoral vein
b. anticubetal vein
c. intenal juglar vein
d. subclavian vein
e. veins on dorsum of a warm hand
169. External carotid artey is differentiated from internal carotid artery
a. more pulsatile
b. branches in neck
c. deep
170. A person after some kind of thermal stress, was found to be unconscious, on examination he has cold clamy extremities, core body temperature 99 F, n has hypotension,, which of the following phenonmenon occurred
a. heat exhaustion
b. heat stroke
c. hypoyhermia
171. A patient has pituitary tumor, in addition to blindness from compression of optic chiasma, it has also eroded lower part of hypo thalamus. Which of the following will result from hypothalamus lesion
a. hyperphagia
b. hyperthermia
c. hypothermia
172. Most common congenital heart disease
a. ASD
b. VSD
c. TOF
d.PDA
173. Which of the following autoimmune disease involves only single organ
a. SLE
b. RA
c. cystic fibrosis
174. EBV causes which malignancy
a. nasopharyngeal carcinoma
b. kaposi sarcoma
c. burkitt’s lymphoma
175. About chalamydia
a. cause choriorretinitis
b. cause trachoma
c. is aerobic organism
d. is club shaped
176. When loop diuretic given, which one of the following is correct
a. dec interstitium osmolality,so dilute uurine is produced
b. dec osmolality of tubular fluid
c. dec calcium in urine
d. dec urea secreted in urine
177. Central artey of retina is related to
a. superior orbital fissure
b. inferior orbital fissure
c. optic canal
d. cavernous sinus
e. facial vein
178. Turbulence in vessel is increased by increase in
a. diameter
b. velocity
c. radius
d. viscosity
179. About broncho pulmonary segment
a. supplied by tertiary bronchiole
b. is independent of each other
c. artey is anterior to bronchus
d. vein is posterior to bronchus
180. Osmlarity increase with increase in
a. number of solute particles
b. size of solute particles
c. molecular weight of solute particles
181. Blood supply of stomach
a. right gastric artery supply lesser curvature
b. right gastroepiploic artey is branch of gastrodudenal artery
c. short gastric artery is branch of hepatic artery
182. What is true regarding fibroadenoma of the breast ?
a. posterior acoustic enhancement in less than 50%
b. is likely to be tender to palpation
c. macro calcifications are usually seen
d. regresses after menopause
e. the presence of a halo is an ominous sign
183. Medullary branch of vertebral artery is damaged on right side, which of the following will result
a. loss of hypoglossal nerve function on same side
b. loss of hypoglossal function on opposite side
c. loss of all sensation on opposite side
d. loss of voluntary movement on opposite side
184. Insulin secretion is decreased by
a. glucagon secretion
b. food intake
c. somatostatin release
d. pituitary gland
185. Connective tissue in all body except head n neck, is derived from
a. ectoderm
b. endoderm
c. mesoderm
d. ecto + meso
e. meso +endo
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