Monday, 8 July 2013

Medicine 2013 FCPS Part-1 Paper

1. Resistance varies indirect proportional to ? 

a. Viscosity
b. Hematocrit
c.length of the vessel
d. radius of the vessel
e. velocity of the blood

Answer is = D

2.The difference of osmolarity between interstitial fluid and plasma is ? 

a.1 mosm/l
b.2.5 mosm/l
c. 3 mosm/l
d. 5 mosm/l
e. No difference 

Answer is = 1 mosm/l

3.Which of the following cranial nerves are parasympathetic ? 

a. 3,4,7,10
b.3 ,7,9,10
c.2,3,6,7
d. 1 ,2 ,5,10

Answer is = b 


4.Regarding QRS complex,what is inappropriate ? 

a.Occurs due to ventricular depolarization
b.has +ve and -ve waves
c.Occurs just before ventricular systole.
d. Indicates atrial depolarization


Answer is = D

5.65% of filtered Na is reabsorbed from 

a.PCT
b.DCT
c.loop of henle.
d.Collecting duct

Answer is a 


6.Venous return depends upon ? 

a.velocity of the blood
b.increased mean systemic filling pressure
c.cardiac output
d.stiffness of vessel

Answer is B

7.Volume remaining in the lungs after tidal volume expiration is ? 

a.residual volume
b.expiratory reserve volume
c.FRC
d.vital capacity
e.TLC

Answers is C


8. Regarding thorax,find out the wrong statement

a.pump handle increases transverse diameter
b.abdominal type of respiration is seen in children
c.diaphragm is important muscle for respiration
d. xiphisternum is located at T 9 vertebrae.

Answer is B

9. In asthmatic patient allergen react directly with ? 

a. mast cells
b. eosinophills 
c.macrophages
d. epithelial cells

Answer is A


10. PTH increases CA re-absorption by acting on ? 

a.pct
b. dct
c. loop of henle
d. collecting duct

Answer is B

11. Oxygen HB-dissociation curve shifts to the left due to ? 

a. increased CO2 
b. decreased PH
c. high altitude 
d. carbon monoxide poisoning.

Answer is D 

12. Elimination of aminoglycosides antibiotics from the body in elderly is decreased due to decreased ? 

a. fat metabolism
b. hepatic metabolism
c. renal excretion
d.plasma protein binding
e. volume of distribution

Answer is C


13.Immune mediated disorders occur due to location of genes on ? 

a.spleen
b.rbc
c.wbc
d.liver
e.kidney

Answer is C

14. Gastric emptying is decreased by

a.gastrin
b.CCK
c.secretin
d.GIP

Answer is B

15. Patient presented in ER with dyspnea ; Ph = 7.13 , Co2 = 55 mm hg , HCO3 = 26 mmol/l , Po2 = 49 mm hg ;  He is K/C of COPD , what is the most likely diagnosis ? 

a. Respiratory acidosis
b. respiratory alkalosis
c.respiratory acidosis with type 1 respiratory failure
d. fully compensated respiratory acidosis
e.respiratory acidosis with type-2 respiratory failure


Answer is E


16. Hamartoma is defined as ? 

a.mass of mature disorganized tissue indigenous to that organ
b. ectopic rest of normal tissue
c. a tumor that can metastasize
d. a malignat tumor that can cause serious complications

Answer is A 


17. The cutting of pituitary stalk will predominately lead to increased levels of which pituitary hormone ? 

a. GH
b. prolactin
c. TSH
d. ACTH
e. FSH and LH

Answer is B 

18. L- DOPA given in the treatment of parkinson's disease leads to decrease in levels of which hormone ?

a. Prolactin
b. GH
c. Cortisol 
d. testosterone


Answer is A


!9. In the presence of ADH, the water is maximally reabsorbed from ? 


a. PCT
b. cortical collecting tubule
c.medullary collecting duct
d. loop of henle
e. early distal tubule

Answer is A

20. Strong chemotactic agent is 

a. C5a
b. C5b
c. C3b
d. opsonin
e. platelet


Answer is A 

21. Carcinoma stains with which of the following ? 

a. desmin
b. keratin
c. vimentin 
d. pas
e. congo red

Answer is B 




22.  Which of the following malignancy is transmitted as autosomal  dominant mode of inheritance ? 

a. ca-calon
b. retinoblastoma
c. ca-breast
d. ca-live

Answer is B


23. A lady is having cervical lymph adenopathy and is diagnosed as a case of lymphoma, which immunological disorder she is most likely having ? 


a. aids
b. sle
c. pan
d. ra
e. sjogren syndrome

Answer is A 

24. First symptom that occurs due to hypopituitarism due to pituitary tumor would be ? 

a. hypothyroidisn
b. hypogonadism
c. hypoglycemia
d. hypoadrenalism 
e. hypovolumia

Answer is B 


25. Which of the following is benign tumor ? 

a. adenoma
b. hepatoma
c. melanoma
d. lymphoma

Answer is  A 


26. Which of the following has least malignant potential  ? 

a. fap
b. metaplastic polyp
c. tubular adenoma
d. villous adenoma

Answer is C 


27. Which of the following statement is "incorrect" about metaplasia ? 

a. one adult cell type replaces another cell type
b. irreversible
c.can occur in lungs
d. can occur in epithelial cells 
e. protective change against chronic irritation

Answer is A 


28. Oxytocin and ADh originates in  ? 


a. neurohypophysis 
b. hypothalamus 
c. adenohypophysis 
d.thalamus 
e. mid brain


Answer is B 

29. Bad news provided by doctor should be ? 

a. in front of nursing staff 
b. by a psychiatrist 
c. at bedside
d. in front of all the family members
e. by the concerned doctor in formal session in exclusivity 

Answer is E 


30.Best way to start communication with patient should be ? 


a. by asking cross questions
b. by asking about illness
c. by asking about name , age, address , and occupation
d. by asking leading questions

Answer c 


31. Hormone which increases protein deposition in skeletal muscles ? 

a. estrogen
b. testosterone
c. cortisol
d. dihydrotestosterone
e. progesterone 

 answer is B 

32. Growth hormone ? 

a. affects metabolism of carbohydrates 
b. causes skeletal and cartilage growth through somatomedins 
c. has half life of 6-20 mins in circulation
d. is a hormone of pituitary gland
e. is a polypeptide

Answer is B

33. Which of the following organ causes bone growth by releasing peptide ? 

a. brain
b. liver.
c.kidney
d.git
e. adrenal cortex

Answer is A 


34. Formation of interstitial fluid increases with decreased ? 

a. capillary hydrostatic pressure
b. capillary permeability
c. interstitial fluid colloid osmotic pressure
d. lymphatic flow
e. plasma colloid osmotic pressure

Answer is E 


35. The post prandial state is characterized by ? 


a. high blood levels of FFA and high levels of glucagon
b. high blood levels of FFA and low levels of glucagon
c. high blood levels of glucose and high levels of insulin 
d. high blood levels of glucose and low levels of insulin 
e. high blood levels of insulin and glucagon

Answer is C 


36 .Which of the following is inappropriate for insulin ? 


a. causes entry of glucose into cells of adipose tissue
b. is anabolic hormone
c. decreases gluconeogenesis
d. causes induction of lipoprotein lipase
e. increases glycogenolysis 

Answer is E 


37.  Correct about ANS ? 

a. all sympathetic are adrenergic
b. all para - sympathetic are cholinergic
c. all sympathetic are cholinergic
d. all para sympathetic are adrenergic 
e. at autonomic ganglia all are adrenergic


Answer is B 


38. Which of the following has highest pH ? 


a. saliva
b. pancreatic juice
c. bile
d.gastric juice

Answer B


39. A 4 year boy presented with clinical features of failure  tl thrive , recurrent sinusitis , otitis media and rti . He also gives h/o chronic diarrhea, there is family h/o such complaints, the most relevant investigation in this case to confirm the dignosis is ? 

a. chloride sweat test
b. fat absorption test
c. jejunal biopsy
d. vit b-12 assay
e. serum immunoglobulin level

Answer is A 

40. Small child present with malabsorption , foul smelling stool , steatorrhea , deficiency of following is likely to occur in this patient ? 


a. folate
b.iron
c. ca
d. vit d
e. vit b-12

Answer is D 


41. Regarding active transport, find out most appropriate ? 

a. occurs in few cells
b. always means Na-K pump
c. always requires glucose
d.does not require energy 
e. is carrier mediated and carriers proteins are enzymatic in nature

Answer is E

42.Tractus-solitarius contains ? 

a. auditory neurons
b. 1st order neurons for taste 
c. 2nd order neurons for taste
d. parasympathetic fibres related to facial nerve

Answer C 

43. Sharp-fast pain is mediated by which of the following fiber ? 

a. c -fiber
b. a-delta
c. beta
d. theta

Answer is B 


44. Regarding thalamus , most appropriate statement is ? 

a. associated with behavior and emotions
b.associated with temperature regulation
c. associated with water regulation
d.plays key role in sexual funtions
e.is relay centre for all somatic and special senses 

Answers is E


45. Facial nerve collects taste information from ant 2/3 of tongue through its chorda tympani branch, functional component of taste sensation is ? 

a.General somatic afferent
b. general visceral afferent
c.general visceral efferent
d.special somatic afferent
e.special visceral afferent


Answer is E


46. Nerve passing through foramen ovale is ?


a.maxially
b.mandibular
c.occulomotor
d.trochlear

Answer is B


47. Patient having deviation of angle of mouth,dribbling of saliva , can not close eye and wrinkle forehead , nerve must likely involved is ? 

a. facial
b. maxillary division of trigeminal nerve
c. auriculo temporal 
d.mandibular division of trigeminal nerve

Answer is A

48. Hairy cell leukoplakia is associated with 


a. hiv
b. fungus
c. all
d. cll

Answer is A


49. Histological characteristic of TB is ? 


a. acid fast bacili 
b. caseation
c.gram+ve staining
d. giant cells

Answer is B


50. Vibration is carried by ? 


a. Pacinian corpuscles 
b. meissners corpuscles
c.ruffini corpuscles
d.nocieptors

Answer is A


51. Static pressure is carried by ? 

a. ruffini corpuscles
b. pacinian corpuscles 
c.meissners corpuscles
d. nociceptors 

Answer is A


52. Myxoid degeneration is mostly associated with 


a. carcinoid valve disease
b.infective endocarditis
c.libman-sack's endocarditis 
d.marantic endocarditis
e.mitral valve prolapse


Answer is B


53. Among st the causes of fatty changes in liver, most frequent in our country is ? 

a. alcohol
b.hbv and hcv
c. halothane
d. obesity
e.starvation


Answer is B

54. Regarding dysplasia, most appropriate ? 


a.disarray of cells, having loss of architecture 
b.pleomorphism
c. increased mitotic figures
d. increase in size of cell

Answer is A



55. Ischemic heart  disease with or with out sequel that doesn't present with characteristic clinical features ? 


a. chronic ihd
b/ prinzmental angina
c.stable angina
d. unstable angina
e. mi 


Answer is B



56. A young chuld on anti-malarial passed cola colored urine , what could be the cause ? 


a. g6pd deficiency 
b. drug reaction 
c. iron deficiency anemia
d. thalessemia


Answer is A 


57. Grade-4 encephalopathy is caused by ?

a. alcohol
b. paracetomol
c. ethylene glycol
d. amphetamine

Answer is B

58. A 40 year male on att for last 3 weeks c/o joint pains , his serum uric acid is raised . which is culprit drug ? 


a. isoniazid 
b. ethambutol
c. pyrazinamide
d. rifampicin
e. streptomycin

Answer is C


59. Drug of choice for traveler's diarrhea ? 


a. aluminium hydroxide
b. dipheno-oxylate
c. metaclopromide
d. sucralfate

Answer is B


60. Angina may be worsened by ? 


a. atropine
b. salbutamol
c.theophylline
d. vasopressin 
e.verapamil


answer is C


61. Synapses are absent in ? 


a.dorsal horn of spinal cord
b. dorsal root ganglia
c.lateral horn of spinal cord
d. sympathetic chain ganglion
e.ventral horn of spinal cord


Answer is B


62. Muscles of back are supplied by ? 

a. dorsal rami of spinal nerves
b.cervical plexus
c. Ventral rami of spinal nerves


Answer is A


63. Type of join between two pubic bones ? 

a. syndesmosis
b.symphysis
c.primary cartilaginous join
d. fibrous joint


answer is B


64. Most appropriate regarding fibro-cartilage ?


a. is present in nose
b. contains type 2 collagen
c. is present in intervertebral discs 

Answer is C


65. Junction b/w two epithelial cells that does not allow free movement of substance is called ? 


a. zona adherence 
b. tight junction
c. desmosomes
d. gap junction

Answer is B


66. Patient has suffered 3rd degree burns to arm and hand , he is worried about which of the following most likely complication ? 


a. wound dehiscence 
b. contracture
c. keloid 
d.traumatic neuroma 


Answer is B 


67. Regarding mid brain find out most appropriate ?


a. cerebral aqueduct forms cavity of mid brain
b. posterior surface is marked by presence of 2 colliculi
c. tectum divides into 2 crus cerebrei
d. trochlear nerve emerges from anterior surface 

Answer is A 


68. Which of the following receives sub-capsular afferents ? 

a. lymph node
b. tonsil
c.thymus
d. spleen
e.payer's patch


69. A polymorph leukocytosis is expected in ?? 

a. appendicular tumor
b. glandular fever
c. mi
d. typhoid and para-typhoid 
e. chronic osteomyelitis


70. Correct about respiratory zone ? 

a. terminal bronchioles to alveoli 
b. alveolar duct and alveolar sac
c. respiratory bronchi to alveoli
d. medium size bronchi

71. End plate fiver of neuro muscular junction contains ? 

a. acetyl cholinestrase
b.pre-synaptic ach vesicle
c. post synaptic ca vesicle
d. synthesizes ach

72. Hepatic pedicle contains ? 

a.hepatic vein and cbd
b. hepatic artery, hepatic vein and cbd
c.portal vein and hepatic duct
d. portal vein , cbd and hepatic artery

73. Basal ganglia complex is unique that it contains ?

a. high copper
b. low copper
c. manganese
d. high mg

74. Regarding vertebra , find out most appropriate ? 

a. lumber vertebrae is heart shaped 
b. C-7 has long spinous process
c. thoracic forms transverse process
d. the thoracic vertebrae is kidney shaped

75. A young lady presented with lump in outer lateral quadrant of breast which of the following group of lymph nodes is involved ?

a. anterior axillary
b. apical
c. posterior
d. internal thoracic

76. right kidney is differentiated from left kidney by ? 

a. color of kidney
b. no of coverings of kidney
c. relations of structures in hilum
d. sufaces and poles in kidney
e. weight and size of kidney

78. PDA is persistent part of the left ? 

a. 4th arch
b. 5th arch
c. 6th arch
d. dorsal aorta
e. ventral aorta

79. Root of the right lung is crossed by ?

a. sub clavian vein
b.arch of aorta
c.azygous vein
d. right pulmonary artey

80. Vessel which supply derivatives of foregut

a. celiac artrey
b. SMA
c. IMA
d. splenic artery

81. Following will not form the boundary of inguinal canal ? 


a. lacunar ligament
b. ext.oblique aponeurosis
c. transversalis fasicia
d. conjoint tendon
e. inguinal ligament


81. Patient treated via conservative surgery for ca colon , best marker for disease progression is ?


a. alpha feto protein
b. cea
c. b-hcg
d. erythropoietin


82. Structure found 2 feet away from ileo-cecal junction at anti - mesenteric border is most likely ?


a. omphalocele
b. meckel's diverticulum
c. volvulus
d.gastochisis
e. intussusceptions

83







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